Protein Alignment CAH2 and Ca5a

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_062166.1
• Gene: Ca5a / 54233
• RGDID: 2243
• Length: 304
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 93/322 - (28%)
• Similarity: 154/322 - (47%)
• Gaps: 76/322 - (23%)

  Fly     8 PFAIV--IAPILICASLVLAQDFGYEGRHGPEHW------SEDYARCS-------------GKHQ 51
            |.||:  :.|  :||:             .|:||      :|.::.|:             |..|
  Rat    14 PLAILRHMGP--LCAT-------------RPQHWRFQHSYAEKHSNCARHPLWTGPVSSPGGTQQ 63

  Fly    52 SPINIDQVSAVEKKFPKLEFFNFKVVPDNLQ--------MTNNGHTVLVKMSYNEDEIPSVRGGP 108
            |||||....:|         ::.|:.|..:.        :.|.|:...|:...:.:| ..:.|||
  Rat    64 SPINIQWTDSV---------YDPKLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEE-SGISGGP 118

  Fly   109 LAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRN-LEYPDFASALDKDHGIAVM 172
            |...    |:.:|||||||..|..|||.:::..|||||||:|..| ::|.::..|...::|:||:
  Rat   119 LGNH----YRLKQFHFHWGATDEWGSEHMVDGHAYPAELHLVHWNSMKYENYKKATTGENGLAVI 179

  Fly   173 AFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEY----ISKSVESYFSYTGSLTTPP 233
            ..|.::|.... ..:...::|.::..|...|.|      |.:    :..:...|::|.|||||||
  Rat   180 GVFLKLGAHHE-ALQRLVDILPEVRHKDTQVTM------GPFDPSCLLPACRDYWTYPGSLTTPP 237

  Fly   234 CSEEVTWIDFTTPIDITEKQLNAFRLLT-----ANDDHLKNNFRPIQPLNDRTLYKNYIEIP 290
            .:|.||||....||:::..||:.||.|.     .:::.:.|||||:|||..|.:..:: ::|
  Rat   238 LAESVTWIVHKMPIEVSPSQLSTFRTLLFSGRGEDEEVMVNNFRPLQPLRGRNVRSSF-QVP 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	86/288 (30%)
Ca5a	NP_062166.1	alpha_CA	60..295	CDD:469577	81/255 (32%)