Protein Alignment CAH2 and Ca3

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_062165.2
• Gene: Ca3 / 54232
• RGDID: 2241
• Length: 260
• Species: Rattus norvegicus
• Alignment Length: 271
• Identity: 88/271 - (32%)
• Similarity: 138/271 - (50%)
• Gaps: 20/271 - (7%)

  Fly    24 LAQDFGYEGRHGPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNLQ-MTNNG 87
            :|:::||...:|||||.|.|....|.:||||.:.....  :..|.|:.::....|.:.: :.|||
  Rat     1 MAKEWGYASHNGPEHWHELYPIAKGDNQSPIELHTKDI--RHDPSLQPWSVSYDPGSAKTILNNG 63

  Fly    88 HTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLR 152
            .|..|......|. ..:|||||:..    |:..|||.|||.:|..|||..::...|.||||:|..
  Rat    64 KTCRVVFDDTFDR-SMLRGGPLSGP----YRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123

  Fly   153 NLEYPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSV--NMTNPLPLGEYI 215
            |.:|..|..||.:..||||:..|.::| :..|.::...:.|.:|..|||..  |..:|    ..:
  Rat   124 NPKYNTFGEALKQPDGIAVVGIFLKIG-REKGEFQILLDALDKIKTKGKEAPFNHFDP----SCL 183

  Fly   216 SKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDDH-----LKNNFRPIQ 275
            ..:...|::|.||.|||||.|.:.|:....|:.::..|:...|.|.|:.::     |..|:||.|
  Rat   184 FPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVGNWRPPQ 248

  Fly   276 PLNDRTLYKNY 286
            |:..|.:..::
  Rat   249 PIKGRVVRASF 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	85/259 (33%)
Ca3	NP_062165.2	alpha_CA_I_II_III_XIII	1..259	CDD:239393	88/269 (33%)
		Involved in proton transfer. /evidence=ECO:0000250|UniProtKB:P07451	64..67		1/2 (50%)