Protein Alignment CAH2 and Car14

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: XP_006501505.1
• Gene: Car14 / 23831
• MGIID: 1344341
• Length: 460
• Species: Mus musculus
• Alignment Length: 296
• Identity: 97/296 - (32%)
• Similarity: 149/296 - (50%)
• Gaps: 25/296 - (8%)

  Fly    16 ILICASLVLAQDFG----YEGRHGPEHWSEDYARCSGKHQSPINIDQVSAV-EKKFPKLEFFNF- 74
            :|:..:.:||.|.|    |||.||.:||...|..|.|..||||||...|.: :...|.::...:
Mouse     6 LLLKVTWILAADGGHHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYD 70

  Fly    75 KVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTI-GSEDLI 138
            ::..:.|.:.||||||.:.:.      |::..|.|..|    |...|.|.|||:..:: |||..|
Mouse    71 QLGTEPLDLHNNGHTVQLSLP------PTLHLGGLPRK----YTAAQLHLHWGQRGSLEGSEHQI 125

  Fly   139 NNRAYPAELHVV-LRNLEYPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKS 202
            |:.|..|||||| ..:..|...:.|..|..|:||:....:||:.....|:...:.|.:|..|.:.
Mouse   126 NSEATAAELHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQK 190

  Fly   203 VNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFR--LLTANDD 265
            .::. |..:.|...:.:|.:|.|.||||||||.:.|.|..|.....|:..||...:  |.:..:|
Mouse   191 TSVP-PFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEED 254

  Fly   266 ---HLKNNFRPIQPLNDRTLYKNYIEI-PIHNMGSI 297
               .|..|:|..||||.||::.::|:. |::..|.:
Mouse   255 PSEPLVQNYRVPQPLNQRTIFASFIQAGPLYTTGEM 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	86/260 (33%)
Car14	XP_006501505.1	alpha_CA_XII_XIV	29..278	CDD:239400	85/259 (33%)