Protein Alignment CAH2 and CA14

DIOPT Version :9

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_036245.1
• Gene: CA14 / 23632
• HGNCID: 1372
• Length: 337
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 93/293 - (31%)
• Similarity: 144/293 - (49%)
• Gaps: 28/293 - (9%)

  Fly    11 IVIAPILICASLVLAQDFG----YEGRHGPEHWSEDYARCSGKHQSPINIDQVSAV-EKKFPKLE 70
            ::.:.:|:....:||.|.|    |||.||.:||...|..|....||||:|...|.. :...|.|:
Human     1 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQ 65

  Fly    71 FFNF-KVVPDNLQMTNNGHTVLVKMSYNEDEIPSV--RGGPLAEKTPLGYQFEQFHFHWGENDTI 132
            ...: :...:.|.:.||||||.:       .:||.  .||     .|..|...|.|.|||:..:.
Human    66 PHGYDQPGTEPLDLHNNGHTVQL-------SLPSTLYLGG-----LPRKYVAAQLHLHWGQKGSP 118

  Fly   133 -GSEDLINNRAYPAELHVVLRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQ 195
             |||..||:.|..||||:|..:.: |...:.|.::..|:||:....:||:.....||...:.|.:
Human   119 GGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHE 183

  Fly   196 IDRKGKSVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFR-- 258
            :..|.:..::. |..|.|.:.|.:..||.|.||||||||.:.|.|..|.....|:.:||...:
Human   184 VRHKDQKTSVP-PFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGT 247

  Fly   259 LLTANDDHLK---NNFRPIQPLNDRTLYKNYIE 288
            |.:..::..|   .|:|.:||||.|.::.::|:
Human   248 LFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQ 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	87/267 (33%)
CA14	NP_036245.1	alpha_CA_XII_XIV	29..278	CDD:239400	83/261 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5563
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.670