DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh7 and Mchr1

DIOPT Version :9

Sequence 1:	NP_524035.2	Gene:	Rh7 / 39389	FlyBaseID:	FBgn0036260	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_113946.1	Gene:	Mchr1 / 83567	RGDID:	619841	Length:	353	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	81/336 - (24%)
Similarity:	145/336 - (43%)	Gaps:	33/336 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 PPKSSTF----LIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPAN---ILVMNLAICDFLMLI 167
            ||::.:.    :||.:::..|.::|.|||:.|||....:..|...:|   |.::||::.|.|.|:
  Rat    30 PPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLL 94

  Fly   168 KCPIAIYNNIKEGP-ALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLR 231
            ..|..|:..:..|. ..|:..|.|...:...|...:...|||:.:|||...|||:...:......
  Rat    95 GMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSM 159

  Fly   232 SYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLT 296
            :.|:|.|:|..||: ::.|.......:..|.| ...|.....|.:.....|....|..|:.:|..
  Rat   160 ATLVICLLWALSFI-SITPVWLYARLIPFPGG-AVGCGIRLPNPDTDLYWFTLYQFFLAFALPFV 222

  Fly   297 SIVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHI 361
            .|..:|..||:.:.::....|.:......:::.....||..::|:.|:||.::          .:
  Rat   223 VITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVL----------QL 277

  Fly   362 TPLGSMIPAL---FCKTAA--------CVDPYLYAATHPRFRVEVRMLF--YGRGVLRRVSTTRS 413
            |.|....|.|   :...||        |::|::|......||..:.:..  ..:|.||.||..::
  Rat   278 TQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQT 342

  Fly   414 SYMTRSRSSFT 424
            :...|:.|..|
  Rat   343 ADEERTESKGT 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	38/125 (30%)
Rh7	NP_524035.2	7tm_1	133..384	CDD:278431	63/265 (24%)
Mchr1	NP_113946.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		7tmA_MCHR1	41..322	CDD:320460	71/292 (24%)
		TM helix 1	42..68	CDD:320460	10/25 (40%)
		TM helix 2	78..104	CDD:320460	8/25 (32%)
		TM helix 3	116..146	CDD:320460	9/29 (31%)
		TM helix 4	158..178	CDD:320460	6/20 (30%)
		TM helix 5	205..234	CDD:320460	8/28 (29%)
		TM helix 6	249..279	CDD:320460	6/39 (15%)
		TM helix 7	290..315	CDD:320460	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010