Protein Alignment Rh7 and mchr1.2

DIOPT Version :10

• Sequence 1: NP_524035.2
• Gene: Rh7 / 39389
• FlyBaseID: FBgn0036260
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001072243.1
• Gene: mchr1.2 / 779692
• XenbaseID: XB-GENE-1018376
• Length: 360
• Species: Xenopus tropicalis
• Alignment Length: 347
• Identity: 76/347 - (21%)
• Similarity: 145/347 - (41%)
• Gaps: 55/347 - (15%)

  Fly   109 EPPKSSTF--LIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPA---NILVMNLAICDFLMLIK 168
            :|..:.|:  :||..::.:|.::|.:||:.||:....:...|..:   :|.::||::.|.|.|:.
 Frog    28 DPSSNVTYASVIMPTVFGVICLLGIIGNSVVIYTVFKKSKFRCSSSVPDIFIINLSVVDLLFLLG 92

  Fly   169 CPIAIYNNIKEGP-ALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRS 232
            .|..|:..:..|. ..|:..|.|...:...|...:...|||:::|||...|:|....:......:
 Frog    93 MPFLIHQLLGNGVWHFGETMCTLITALDTNSQFTSTYILTAMSIDRYLATVYPFTSAKYRKPPIA 157

  Fly   233 YLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTS 297
            .::|.::|..| |.::.|.......:.:|.|.| .|.....|.|.....:....|..|:.||...
 Frog   158 IMVICILWVLS-LLSITPVWMYARLIALPGGVL-GCGITLPNPESDIYWYTLYQFFLAFAIPFAV 220

  Fly   298 IVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHIT 362
            |..:|..||..:.::..:.:::......:|:.....||..::|:.|:|:.::          .|.
 Frog   221 ISVAYRRILLKMASSEALTAHRSSRIRTKKVTRTAIAICLVFFICWAPFYVL----------QII 275

  Fly   363 PLGSMIPAL-----FCKTA------ACVDPYLY-----------------AATHPRFRVEVRMLF 399
            .|....|.|     :|...      :|::|::|                 |..||..|  :||.|
 Frog   276 QLVMDQPTLAFHYAYCVAISMGYANSCINPFIYIILCETFRRRFIVSVQPAEDHPESR--IRMKF 338

  Fly   400 -------YGRGVLRRVSTTRSS 414
                   .|:.:|:.|..:..|
 Frog   339 RTDPPSGSGQPLLQLVPVSTGS 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_GPCRs	118..395	CDD:475119	67/308 (22%)
		TM helix 1	119..143	CDD:320207	7/23 (30%)
		TM helix 2	152..173	CDD:320207	7/20 (35%)
		TM helix 3	189..211	CDD:320207	5/21 (24%)
		TM helix 4	234..250	CDD:320207	4/15 (27%)
		TM helix 5	280..303	CDD:320207	5/22 (23%)
		TM helix 6	329..351	CDD:320207	5/21 (24%)
		TM helix 7	363..388	CDD:320207	8/52 (15%)
mchr1.2	NP_001072243.1	7tmA_MCHR1	38..319	CDD:320460	63/292 (22%)
		TM helix 1	39..65	CDD:320460	8/25 (32%)
		TM helix 2	75..101	CDD:320460	8/25 (32%)
		TM helix 3	113..143	CDD:320460	9/29 (31%)
		TM helix 4	155..175	CDD:320460	4/20 (20%)
		TM helix 5	202..231	CDD:320460	8/28 (29%)
		TM helix 6	246..276	CDD:320460	7/39 (18%)
		TM helix 7	287..312	CDD:320460	4/24 (17%)