DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh7 and SSTR5

DIOPT Version :9

Sequence 1:	NP_524035.2	Gene:	Rh7 / 39389	FlyBaseID:	FBgn0036260	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_001044.1	Gene:	SSTR5 / 6755	HGNCID:	11334	Length:	364	Species:	Homo sapiens

Alignment Length:	331	Identity:	79/331 - (23%)
Similarity:	138/331 - (41%)	Gaps:	48/331 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 PPKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPIAIY 174
            |...:..:::..||.|:...|..||..||::......::|..||.::|||:.|.|.::..|....
Human    34 PSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLAT 98

  Fly   175 NNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLR----RCSRLRSYLI 235
            .|.......|.:.|||...:.|::...::..||.:::|||..|||||...|    |.::|.|...
Human    99 QNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAA 163

  Fly   236 ILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFF----VAAYCIPLT 296
            .:|..|.|     :|.|   :...|.||  .||:..:   ..|..::.|:|.    |..:..||.
Human   164 WVLSLCMS-----LPLL---VFADVQEG--GTCNASW---PEPVGLWGAVFIIYTAVLGFFAPLL 215

  Fly   297 SIVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHI 361
            .|...|..|: |...|:.::....:.::|:|:..:|..::.::...|.|:..|          :|
Human   216 VICLCYLLIV-VKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTV----------NI 269

  Fly   362 TPLGSMIP------------ALFCKTAACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSS 414
            ..|...:|            .:.....:|.:|.||......||...:.:.    .||:.|..:.:
Human   270 VNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVL----CLRKGSGAKDA 330

  Fly   415 YMTRSR 420
            ..|..|
Human   331 DATEPR 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	38/125 (30%)
Rh7	NP_524035.2	7tm_1	133..384	CDD:278431	65/270 (24%)
SSTR5	NP_001044.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		7tm_4	54..319	CDD:304433	70/288 (24%)
		7tm_1	57..304	CDD:278431	65/270 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..364		2/10 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140656
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940