Protein Alignment Rh7 and oprd1b

DIOPT Version :10

• Sequence 1: NP_524035.2
• Gene: Rh7 / 39389
• FlyBaseID: FBgn0036260
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_997920.2
• Gene: oprd1b / 336529
• ZFINID: ZDB-GENE-030131-8473
• Length: 375
• Species: Danio rerio
• Alignment Length: 378
• Identity: 80/378 - (21%)
• Similarity: 159/378 - (42%)
• Gaps: 74/378 - (19%)

  Fly    77 LSNYS-NYPSYIHYRDKYDLSYI---AKVNPFW----LQFEPPKSSTFLIMA----ALYCLISVV 129
            :|::| .||.::|     :.|::   |.:...|    .:.:..:.|:.:.:|    |||.:|.||
Zfish     8 VSDFSERYPLFLH-----NSSFLEEPAGLLSNWSGGSSELKAVRGSSAVAIAVSITALYSVICVV 67

  Fly   130 GCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPIAIYNNIKEGPALGDIACRLYGFV 194
            |.|||..|::.......::|..||.:.|||:.|.|.....|......:......|::.|::...:
Zfish    68 GLVGNVLVMYGVVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMGTWPFGELLCKVVIAI 132

  Fly   195 GGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYS-------FLFAVMPAL 252
            ...:...:|.|||.:::|||..|.||::.|...:.:::.:|.:.:|..|       .:.||...|
Zfish   133 DYYNMFTSIFTLTMMSVDRYIAVCHPVRALDFRTPVKAKIINICVWILSSAVGFPVMVMAVTKEL 197

  Fly   253 DIGLSVYV-----PEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTA 312
            |.|.::.:     ||.:..|             :.....|:.|:..|:..|...|..::..:.:.
Zfish   198 DSGKTICMLKFPDPEWYWDT-------------VTKICVFIFAFVFPVLVITVCYGLMILRLKSV 249

  Fly   313 SRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSP-YAIVAMMGVFGLER---------HI-TPLGS 366
            ..:..:|:|.:..:::..:|..::..:.:.|:| :..:.:..|..:::         |: ..||.
Zfish   250 RLLSGSKEKDRNLRRITRMVLVVVAAFIICWTPIHIFIIVKTVVEIDQKNLLVVACWHLCIALGY 314

  Fly   367 MIPALFCKTAACVDPYLYAATHPRF-------------RVEVRMLFYGRGVLR 406
            |..:|        :|.|||.....|             |:|.......|.|:|
Zfish   315 MNSSL--------NPVLYAFLDENFKRCFREFCLPFRTRIEQNSFSKARSVIR 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_GPCRs	118..395	CDD:475119	67/316 (21%)
		TM helix 1	119..143	CDD:320207	12/27 (44%)
		TM helix 2	152..173	CDD:320207	8/20 (40%)
		TM helix 3	189..211	CDD:320207	4/21 (19%)
		TM helix 4	234..250	CDD:320207	5/22 (23%)
		TM helix 5	280..303	CDD:320207	4/22 (18%)
		TM helix 6	329..351	CDD:320207	3/22 (14%)
		TM helix 7	363..388	CDD:320207	8/24 (33%)
oprd1b	NP_997920.2	7tmA_Delta_opioid_R	55..335	CDD:320217	65/300 (22%)
		TM helix 1	56..82	CDD:320217	11/25 (44%)
		TM helix 2	89..115	CDD:320217	8/25 (32%)
		TM helix 3	126..156	CDD:320217	8/29 (28%)
		TM helix 4	168..190	CDD:320217	3/21 (14%)
		TM helix 5	215..245	CDD:320217	6/42 (14%)
		TM helix 6	264..290	CDD:320217	3/25 (12%)
		TM helix 7	303..328	CDD:320217	9/32 (28%)