DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rh7 and Ptgdr2

DIOPT Version :9

Sequence 1:NP_524035.2 Gene:Rh7 / 39389 FlyBaseID:FBgn0036260 Length:483 Species:Drosophila melanogaster
Sequence 2:NP_001012070.1 Gene:Ptgdr2 / 309212 RGDID:1311986 Length:403 Species:Rattus norvegicus


Alignment Length:384 Identity:93/384 - (24%)
Similarity:146/384 - (38%) Gaps:79/384 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 LSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMF 141
            |.|:||  |.:.|.|.                         :...|:.|.|::|.|.|..::|:.
  Rat    19 LPNHSN--SSLRYIDH-------------------------VSVLLHGLASLLGLVENGLILFVV 56

  Fly   142 ANRKSLRTPANILVMNLAICDFLMLIKCPIAIY-NNIKEGPALGDIACRLYGFVGGLSGTCAIGT 205
            ..|.. :|.....|::||:.|.|.....|...| ..:.....||...|:|:..|..|:...:...
  Rat    57 GCRMR-QTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFL 120

  Fly   206 LTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAV--------MPALDIGLSVYVPE 262
            |:||:|||...||.|:......:...::.:.|::|..:.|..|        :|..|..:..|...
  Rat   121 LSAISLDRCLQVVRPVWAQNHRTVAAAHRVCLMLWALAVLNTVPYFVFRDTIPRRDGRIMCYYNM 185

  Fly   263 GFL-------TTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNKD 320
            ..|       |||  ||..|.:....|:     .|:.:||..|..|:        .|..:|.:..
  Rat   186 LLLNPGSDRDTTC--DYRQKALAVSKFL-----LAFMVPLAIIASSH--------VAVSLQLHHR 235

  Fly   321 KAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERH-ITPLGSM----IP-----ALFCKT 375
            ..:...:...:||||:..:.|.|.||.|.:::..   ..| :|.|..:    :|     |.|   
  Rat   236 GRQRTGRFVRLVAAIVVAFILCWGPYHIFSLLEA---RAHSVTTLRQLASRGLPFVTSLAFF--- 294

  Fly   376 AACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSSYMT--RSRSSFTHRLRTSTT 432
            .:.|:|.||..|.|....::|....  .||..|....|...|  ..|....||.|.|:|
  Rat   295 NSVVNPLLYVLTCPDMLHKLRRSLL--TVLESVLVEDSDLSTGPGKRCRRRHRRRASST 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh7NP_524035.2 7tm_4 125..>247 CDD:304433 33/122 (27%)
7tm_1 133..384 CDD:278431 65/276 (24%)
Ptgdr2NP_001012070.1 7tm_GPCRs 32..314 CDD:421689 74/328 (23%)
TM helix 1 33..59 CDD:410628 7/25 (28%)
TM helix 2 65..90 CDD:410628 7/24 (29%)
TM helix 3 103..133 CDD:410628 10/29 (34%)
TM helix 4 145..165 CDD:410628 4/19 (21%)
TM helix 5 202..227 CDD:410628 7/37 (19%)
TM helix 6 238..268 CDD:410628 9/29 (31%)
TM helix 7 282..307 CDD:410628 7/27 (26%)
Involved in the recycling of CRTH2. /evidence=ECO:0000250 329..332 1/2 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..353 7/20 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 384..403
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166334353
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24229
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.030

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