Protein Alignment Rh7 and NPBWR1

DIOPT Version :9

• Sequence 1: NP_524035.2
• Gene: Rh7 / 39389
• FlyBaseID: FBgn0036260
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_005276.2
• Gene: NPBWR1 / 2831
• HGNCID: 4522
• Length: 328
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 78/301 - (25%)
• Similarity: 131/301 - (43%)
• Gaps: 46/301 - (15%)

  Fly   122 LYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPIAIYNNIKEGPALGDI 186
            :|.:|..||..||:.|:::......::|..|:.::||||.|.|..:..||.|.:.:......|::
Human    43 VYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGEL 107

  Fly   187 ACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRS--YLIILLIWCYSFL---- 245
            .|:|...:...:...::..||.::.|||.||:...:..|...|..|  ..:.|.:|....|
Human   108 MCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLP 172

  Fly   246 FAVMPALD-------IGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYF 303
            |||...||       ..|....||.|....|          |::.   .|..:.||:::|...|.
Human   173 FAVFARLDDEQGRRQCVLVFPQPEAFWWRAS----------RLYT---LVLGFAIPVSTICVLYT 224

  Fly   304 YILKVVFTASRIQSN-KDKAKTEQKLAFIVAAIIGLWFLAWSPY---AIVAMMG-------VFGL 357
            .:| ....|.|:.|: |...:.::::.|:|.||:.:..|.|:||   .:||:..       |..:
Human   225 TLL-CRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAI 288

  Fly   358 ERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVRML 398
            ...||.|.        ...:|::|:|||.....||..:|.|
Human   289 SYFITSLS--------YANSCLNPFLYAFLDASFRRNLRQL 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	33/127 (26%)
		7tm_1	133..384	CDD:278431	67/274 (24%)
NPBWR1	NP_005276.2	7tmA_NPBWR	47..318	CDD:320215	75/292 (26%)
		TM helix 2	72..98	CDD:320215	10/25 (40%)
		TM helix 3	109..139	CDD:320215	8/29 (28%)
		TM helix 4	153..175	CDD:320215	5/21 (24%)
		TM helix 5	200..229	CDD:320215	8/42 (19%)
		TM helix 6	244..274	CDD:320215	8/29 (28%)
		TM helix 7	286..311	CDD:320215	8/32 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940