DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh7 and Gpr149

DIOPT Version :9

Sequence 1:	NP_524035.2	Gene:	Rh7 / 39389	FlyBaseID:	FBgn0036260	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_796320.2	Gene:	Gpr149 / 229357	MGIID:	2443628	Length:	732	Species:	Mus musculus

Alignment Length:	234	Identity:	55/234 - (23%)
Similarity:	89/234 - (38%)	Gaps:	37/234 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 TGLSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIF 139
            :.|:|.||.....|...:.||            ...|.:.| |.:..|.|::::...||:.|.:.
Mouse     6 SNLTNDSNLWKASHNSTETDL------------MNSPATLT-LSLFCLICIMTLAALVGSIFSLV 57

  Fly   140 MFANRKSLRTPANILVMNLAICDFLMLIKCPIAIYNNI---KEGPALGDIACRLYGFVGGLSGTC 201
            .....: .||..:|||.:.::.|.|.::.  :||:..:   ||........|.....:....|..
Mouse    58 SLLTMQ-YRTVLSILVTSWSVDDLLSVLS--VAIFMVLQWPKEAQGYFQSLCTTSALLYMCQGLS 119

  Fly   202 AIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYL-IILLIWCYSFLFAVMPALDIGLSVYVPEGFL 265
            :....|.|....:..:...::......||...| :.|.:|..|.|.|.:|....|:.|..|.|.|
Mouse   120 SNLKATLIVCYNFYTMNRTVESQSSSWRLGQVLGVTLTVWAVSLLLASLPLCGWGVFVRTPWGCL 184

  Fly   266 TTCSFDYLNKEMPARIFMALFFV--------AAYCIPLT 296
            |.||..|:         :.||.|        |...:|||
Mouse   185 TDCSSPYV---------LLLFAVYASAFGLLAVLSVPLT 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	25/125 (20%)
Rh7	NP_524035.2	7tm_1	133..384	CDD:278431	42/176 (24%)
Gpr149	NP_796320.2	7tm_1	56..>211	CDD:278431	37/166 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	281..302
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	501..526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030