Protein Alignment Rh7 and Mchr1

DIOPT Version :10

• Sequence 1: NP_524035.2
• Gene: Rh7 / 39389
• FlyBaseID: FBgn0036260
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_660114.1
• Gene: Mchr1 / 207911
• MGIID: 2180756
• Length: 353
• Species: Mus musculus
• Alignment Length: 342
• Identity: 84/342 - (24%)
• Similarity: 148/342 - (43%)
• Gaps: 33/342 - (9%)

  Fly   104 FWLQFEPPKSSTF----LIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPAN---ILVMNLAIC 161
            |.|...||::.:.    :||.:::..|.::|.|||:.|||....:..|...:|   |.::||::.
Mouse    24 FTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVV 88

  Fly   162 DFLMLIKCPIAIYNNIKEGP-ALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLR 225
            |.|.|:..|..|:..:..|. ..|:..|.|...:...|...:...|||:|:|||...|||:...:
Mouse    89 DLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTK 153

  Fly   226 RCSRLRSYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAA 290
            ......:.|:|.|:|..||: ::.|.......:..|.| ...|.....|.:.....|....|..|
Mouse   154 FRKPSMATLVICLLWALSFI-SITPVWLYARLIPFPGG-AVGCGIRLPNPDTDLYWFTLYQFFLA 216

  Fly   291 YCIPLTSIVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVF 355
            :.:|...|..:|..||:.:.::....|.:......:::.....||..::|:.|:||.::
Mouse   217 FALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVL------ 275

  Fly   356 GLERHITPLGSMIPAL---FCKTAA--------CVDPYLYAATHPRFRVEVRMLF--YGRGVLRR 407
                .:|.|....|.|   :...||        |::|::|......||..:.:..  ..:|.||.
Mouse   276 ----QLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRT 336

  Fly   408 VSTTRSSYMTRSRSSFT 424
            ||..:::...|:.|..|
Mouse   337 VSNAQTADEERTESKGT 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_GPCRs	118..395	CDD:475119	72/291 (25%)
		TM helix 1	119..143	CDD:320207	9/23 (39%)
		TM helix 2	152..173	CDD:320207	8/23 (35%)
		TM helix 3	189..211	CDD:320207	5/21 (24%)
		TM helix 4	234..250	CDD:320207	6/15 (40%)
		TM helix 5	280..303	CDD:320207	5/22 (23%)
		TM helix 6	329..351	CDD:320207	6/21 (29%)
		TM helix 7	363..388	CDD:320207	8/35 (23%)
Mchr1	NP_660114.1	7tmA_MCHR1	41..322	CDD:320460	72/292 (25%)
		TM helix 1	42..68	CDD:320460	10/25 (40%)
		TM helix 2	78..104	CDD:320460	8/25 (32%)
		TM helix 3	116..146	CDD:320460	10/29 (34%)
		TM helix 4	158..178	CDD:320460	6/20 (30%)
		TM helix 5	205..234	CDD:320460	8/28 (29%)
		TM helix 6	249..279	CDD:320460	6/39 (15%)
		TM helix 7	290..315	CDD:320460	5/24 (21%)