DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh7 and Sstr5

DIOPT Version :9

Sequence 1:	NP_524035.2	Gene:	Rh7 / 39389	FlyBaseID:	FBgn0036260	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_001177937.1	Gene:	Sstr5 / 20609	MGIID:	894282	Length:	362	Species:	Mus musculus

Alignment Length:	317	Identity:	89/317 - (28%)
Similarity:	149/317 - (47%)	Gaps:	31/317 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 WLQFEP--PKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLI 167
            |...:|  |..:..:::..||.|:..||..||..||::......::|..|:.::|||:.|.|.::
Mouse    24 WSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRYAKMKTVTNVYILNLAVADVLFML 88

  Fly   168 KCP-IAIYNNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLR----RC 227
            ..| :|..|.:...| .|...|||...:.|::...:|..|..:::|||..|||||:..|    |.
Mouse    89 GLPFLATQNAVSYWP-FGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRV 152

  Fly   228 SRLRSYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFF----V 288
            ::|.|    ..:|.:|.|.: :|.|   :...|.||: .||:   |:...|..::.|.|.    |
Mouse   153 AKLAS----AAVWVFSLLMS-LPLL---VFADVQEGW-GTCN---LSWPEPVGLWGAAFITYTSV 205

  Fly   289 AAYCIPLTSIVYSYFYI-LKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMM 352
            ..:..||..|...|..| :||.....|:.|:: :.::|:|:..:|..::.::...|.|:.||.::
Mouse   206 LGFFGPLLVICLCYLLIVVKVKAAGMRVGSSR-RRRSERKVTRMVVVVVLVFVGCWLPFFIVNIV 269

  Fly   353 GV-FGLERHITPLGSMIPALFCKTA-ACVDPYLYAATHPRFRVEVR---MLFYGRGV 404
            .: |.|....|..|.....:....| :|.:|.||......||...|   .|..|.||
Mouse   270 NLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKALCLRRGYGV 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	40/126 (32%)
Rh7	NP_524035.2	7tm_1	133..384	CDD:278431	72/262 (27%)
Sstr5	NP_001177937.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24		89/317 (28%)
		7tm_4	48..>227	CDD:304433	57/191 (30%)
		7tm_1	54..303	CDD:278431	72/262 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	330..362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030