DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh7 and Olfr32

DIOPT Version :9

Sequence 1:	NP_524035.2	Gene:	Rh7 / 39389	FlyBaseID:	FBgn0036260	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_035110.1	Gene:	Olfr32 / 18331	MGIID:	109303	Length:	308	Species:	Mus musculus

Alignment Length:	342	Identity:	69/342 - (20%)
Similarity:	120/342 - (35%)	Gaps:	98/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 FEPP--KSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFL----ML 166
            |:.|  :...|::...:| |.:|   :||..::......|||.:|....:..|::.:.|    ::
Mouse    15 FQDPDVQKVCFVLFLPVY-LATV---LGNGLIVVTVNISKSLYSPMYFFLNYLSLVEILYSSTVV 75

  Fly   167 IKCPIAIYNNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLR 231
            .|....:.|.||   .:....|....|.....|...|..||.:|.|||..:..||......||.:
Mouse    76 PKFITDLLNKIK---TISPKGCLAQIFFFHFFGVTEILLLTVMAYDRYVAICKPLYYTTIMSRPK 137

  Fly   232 SYLIILLIWCYSF------LFAVMP-------ALD-------------------IGLSVYVPEGF 264
            .:.::...|...|      :|..:|       .:|                   :|:.::|..|.
Mouse   138 CHRLVAGSWVGGFFHSIIQIFITLPLPFCGPNVIDHYFCDLHPLFKLACTDTFVVGVIMFVNSGL 202

  Fly   265 LTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNKDKAKTEQKLA 329
            .:..||              ||.|::|.:    |:|:.           |..|.:.:.|.....|
Mouse   203 FSVFSF--------------LFLVSSYIV----ILYNL-----------RNHSAEGRRKALSTCA 238

  Fly   330 ---FIVAAIIG----LWFLAWSPYAIVAMMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAAT 387
               .:|....|    |:....|.|....::.||  ...|||:              ::|.:|...
Mouse   239 SHIMVVVLFFGPAIFLYLRPASTYTEDKLVAVF--YTVITPM--------------LNPIIYTLR 287

  Fly   388 HPRFRVEVRMLFYGRGV 404
            :...:..||.| :|:.|
Mouse   288 NAEVKNAVRKL-WGKKV 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_4	125..>247	CDD:304433	30/131 (23%)
Rh7	NP_524035.2	7tm_1	133..384	CDD:278431	57/293 (19%)
Olfr32	NP_035110.1	7tmA_OR4A-like	22..288	CDD:320605	62/317 (20%)
		TM helix 1	23..49	CDD:320605	6/29 (21%)
		TM helix 2	56..82	CDD:320605	3/25 (12%)
		TM helix 3	94..124	CDD:320605	10/29 (34%)
		TM helix 4	137..158	CDD:320605	2/20 (10%)
		TM helix 5	192..222	CDD:320605	11/47 (23%)
		TM helix 6	228..258	CDD:320605	5/29 (17%)
		TM helix 7	263..288	CDD:320605	7/40 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000