Protein Alignment Rh7 and npr-16

DIOPT Version :10

• Sequence 1: NP_524035.2
• Gene: Rh7 / 39389
• FlyBaseID: FBgn0036260
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001355490.1
• Gene: npr-16 / 180643
• WormBaseID: WBGene00006864
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 358
• Identity: 82/358 - (22%)
• Similarity: 139/358 - (38%)
• Gaps: 70/358 - (19%)

  Fly   117 LIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPI--AIYNNIKE 179
            |.:...:.|:..:|.| |..:|.:...|..||:..|:.::.|.:.||:.|....:  |...|.|.
 Worm    20 LALTVTHLLLVALGSV-NLIIILLIITRPYLRSITNVYMIGLCLADFIYLADLILVAATSLNGKS 83

  Fly   180 GPALGDIACRLYGFVGGLSGTCAIGTLTAI------ALDRYNVVVHPLQPLRRCSRLRSYLIIL- 237
            .| .|...|.|:      .||.|.|...::      |.|||..:...    ..|.|.|:|...:
 Worm    84 WP-FGPTICHLF------HGTEATGKYASVLFVVLLAADRYIAMCKS----DLCGRYRTYRTAIF 137

  Fly   238 ---LIWCYSFLFAVMPALDIGLSVYVP---------------EGFLTTCSFDYLNKEMPARIFMA 284
               |.|..:|:      ..:.|.||..               |...|.| ..:......|:.:::
 Worm   138 LSGLAWIAAFI------CSLPLYVYADEIKVRMRPKNGTDSIENNHTLC-IAHWPSPPHAQWYIS 195

  Fly   285 LFFVAAYCIPLTSIVYSYFYILKVVFTAS----RIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSP 345
            :..|..:.:|...|.|.|:::...:..|:    |:..||....:.|::...|..::....|.|||
 Worm   196 VCSVMIFILPGLVIFYCYYHVFCKLREAAKGSRRLHRNKRSRSSYQRVTRSVQRVVLFHLLCWSP 260

  Fly   346 Y-------AIVAMMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVR-MLFYGR 402
            :       ||..:.....|.|.|..:..:.|.:.|    .::|.|||.....||...: :||:.|
 Worm   261 FWLFNLFSAIFRVRITTQLMRIIVNIIHLFPYVNC----ALNPVLYAYRAENFRTAFKSLLFWSR 321

  Fly   403 GVLRRVSTTRSSYM-----TRSRSSFTHRLRTS 430
               |.||:..:..:     .||.|:.|:...:|
 Worm   322 ---RSVSSKLNRPLPLPEDVRSTSASTYYRNSS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh7	NP_524035.2	7tm_GPCRs	118..395	CDD:475119	70/314 (22%)
		TM helix 1	119..143	CDD:320207	5/23 (22%)
		TM helix 2	152..173	CDD:320207	5/22 (23%)
		TM helix 3	189..211	CDD:320207	5/27 (19%)
		TM helix 4	234..250	CDD:320207	3/19 (16%)
		TM helix 5	280..303	CDD:320207	4/22 (18%)
		TM helix 6	329..351	CDD:320207	7/28 (25%)
		TM helix 7	363..388	CDD:320207	6/24 (25%)
npr-16	NP_001355490.1	7tm_classA_rhodopsin-like	45..305	CDD:410626	63/281 (22%)
		TM helix 2	53..79	CDD:410626	6/25 (24%)
		TM helix 3	91..121	CDD:410626	10/35 (29%)
		TM helix 4	134..153	CDD:410626	3/24 (13%)
		TM helix 5	190..215	CDD:410626	6/24 (25%)
		TM helix 6	238..268	CDD:410626	6/29 (21%)
		TM helix 7	281..305	CDD:410626	8/27 (30%)