DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rh7 and Ptgdr2

DIOPT Version :9

Sequence 1:NP_524035.2 Gene:Rh7 / 39389 FlyBaseID:FBgn0036260 Length:483 Species:Drosophila melanogaster
Sequence 2:NP_034092.1 Gene:Ptgdr2 / 14764 MGIID:1330275 Length:382 Species:Mus musculus


Alignment Length:383 Identity:93/383 - (24%)
Similarity:152/383 - (39%) Gaps:82/383 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 LSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMF 141
            |.|:||  |.:.|.|.                         :...|:.|.|::|.|.|..::|:.
Mouse    19 LPNHSN--SSLRYIDH-------------------------VSVLLHGLASLLGLVENGLILFVV 56

  Fly   142 ANRKSLRTPANILVMNLAICDFLMLIKCPIAIY-NNIKEGPALGDIACRLYGFVGGLSGTCAIGT 205
            ..|.. :|.....|::||:.|.|.....|...| ..:.....||...|:|:..|..|:...:...
Mouse    57 GCRMR-QTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFL 120

  Fly   206 LTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAV--------MPALDIGLSVYV-- 260
            |:||:|||...||.|:......:...::.:.|::|..:.|..:        :|.||..:..|.  
Mouse   121 LSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNL 185

  Fly   261 ------PEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNK 319
                  |:.. |||  ||..|.:....|:     .|:.:||..|..|:      |..:.|:. ::
Mouse   186 LLWNPGPDRD-TTC--DYRQKALAVSKFL-----LAFMVPLAIIASSH------VAVSLRLH-HR 235

  Fly   320 DKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERH-ITPLGSM----IP-----ALFCK 374
            .:.:| .:...:||||:..:.|.|.||.|.:::..   ..| :|.|..:    :|     |.|  
Mouse   236 GRQRT-GRFVRLVAAIVVAFVLCWGPYHIFSLLEA---RAHSVTTLRQLASRGLPFVTSLAFF-- 294

  Fly   375 TAACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSSYMTRSRSSFTHRLRTSTT 432
             .:.|:|.||..|.|....::|...  |.||..|....|.   :|......|.|.|:|
Mouse   295 -NSVVNPLLYVFTCPDMLYKLRRSL--RAVLESVLVEDSD---QSGGLRNRRRRASST 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh7NP_524035.2 7tm_4 125..>247 CDD:304433 33/122 (27%)
7tm_1 133..384 CDD:278431 66/277 (24%)
Ptgdr2NP_034092.1 7tm_GPCRs 32..314 CDD:391938 75/329 (23%)
TM helix 1 34..58 CDD:341315 7/23 (30%)
TM helix 2 66..87 CDD:341315 6/20 (30%)
TM helix 3 104..126 CDD:341315 6/21 (29%)
TM helix 4 149..165 CDD:341315 3/15 (20%)
TM helix 5 203..226 CDD:341315 7/33 (21%)
TM helix 6 241..266 CDD:341315 9/24 (38%)
TM helix 7 282..307 CDD:341315 7/27 (26%)
Involved in the recycling of CRTH2. /evidence=ECO:0000250 329..332 1/5 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830636
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24229
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.030

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