DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrx-IV and CG6763

DIOPT Version :9

Sequence 1:	NP_524034.2	Gene:	Nrx-IV / 39387	FlyBaseID:	FBgn0013997	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	182	Identity:	38/182 - (20%)
Similarity:	68/182 - (37%)	Gaps:	64/182 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1003 GVNLRSS----SIIRYEFEGSFR----STIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISN 1059
            |:..:||    .::.||..|:|.    :||...|......|..: |:...|..   :|::|:..|
  Fly   109 GLPTQSSRWPNGVVPYEIRGNFNARDMATIENAIGEYHRRTCIR-FVKRSSER---DYISIRGDN 169

  Fly  1060 SG--------------HLR---CVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNGGSTVVLKVD 1107
            ||              :|:   |:...|....|::     ..||..|:.:.|.::|
  Fly   170 SGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELM-----HALGFLHEQNRMERDG--------- 220

  Fly  1108 NYEPVEYNFDIKASADAQFNNIQ----------------YMYIGKNESMTDG 1143
             |..::|| ::::||   .||.:                .|:..||....:|
  Fly   221 -YVAIQYN-NVQSSA---MNNFEKAARTEAFGVPYDYGSVMHYSKNAFSING 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrx-IV	NP_524034.2	FA58C	46..185	CDD:214572
		FA58C	57..184	CDD:238014
		LamG	192..340	CDD:238058
		LamG	376..514	CDD:238058
		EGF	546..575	CDD:278437
		Laminin_G_2	824..943	CDD:280389
		EGF_CA	966..998	CDD:238011
		Laminin_G_2	1032..1156	CDD:280389	28/145 (19%)
		4.1m	1239..1255	CDD:128590
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	35/175 (20%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	35/172 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444947
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930