DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrx-IV and CG11865

DIOPT Version :9

Sequence 1:	NP_524034.2	Gene:	Nrx-IV / 39387	FlyBaseID:	FBgn0013997	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	52/230 - (22%)
Similarity:	87/230 - (37%)	Gaps:	75/230 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   912 ALHLTSD--LVIGATTEYRDGYVGCIRALLLNGKMV-DLKEYSKRG---LY----GISTGCVGRC 966
            ::.|..|  ::|....:|.:|.        |.|::| ...||..:|   :|    |.|:..:...
  Fly    21 SIKLQEDDIILISEQLQYFEGN--------LEGRVVKSWSEYYWKGRTLVYSYAGGFSSLDIASI 77

  Fly   967 ESNPC-LNNGTCIE--------------RYDGYSCDCRWS--AFKGPICADE---IGVNLRSSSI 1011
            ||... :::.||::              :.:|..|   ||  .:.|.  ||:   :|....|:..
  Fly    78 ESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGC---WSYVGYLGR--ADQTLNLGSGCMSNRT 137

  Fly  1012 IRYEFEGSFRSTIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISN--SGHLRCVFDFGFERQ 1074
            |::|...:.                  ||....|.....:|:.||..|  |||     :..|:|.
  Fly   138 IQHELLHAL------------------GFFHTHSDPQRDKYVRIQTDNIRSGH-----EHNFQRL 179

  Fly  1075 EIIFPKKHFGLGQYHD--MHF----MRKNGGSTVV 1103
            . .....::|.|..:|  ||:    ..|||.||:|
  Fly   180 R-ANGVTNYGFGYDYDSIMHYGPFAFSKNGQSTIV 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrx-IV	NP_524034.2	FA58C	46..185	CDD:214572
		FA58C	57..184	CDD:238014
		LamG	192..340	CDD:238058
		LamG	376..514	CDD:238058
		EGF	546..575	CDD:278437
		Laminin_G_2	824..943	CDD:280389	6/32 (19%)
		EGF_CA	966..998	CDD:238011	9/48 (19%)
		Laminin_G_2	1032..1156	CDD:280389	23/80 (29%)
		4.1m	1239..1255	CDD:128590
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	42/187 (22%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	42/185 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444836
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930