DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrx-IV and CG15255

DIOPT Version :9

Sequence 1:	NP_524034.2	Gene:	Nrx-IV / 39387	FlyBaseID:	FBgn0013997	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	48/230 - (20%)
Similarity:	73/230 - (31%)	Gaps:	76/230 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   796 NVVTFRIADASINLPPFDMGHSGDIY-----------LEFR-TTQENSVIFHATGPTDYIKLSLN 848
            |||.:||:|      .||..|...|.           |.|| .|.|:......|        :.:
  Fly    71 NVVVYRISD------DFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVT--------AKS 121

  Fly   849 GGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKAEVREPPGPVRAL 913
            ||......||.....:.:.:   |.|.:..:.               .|:|..|.....|   ..
  Fly   122 GGCYTAVGYQGAPQEMNLEI---YPLGEGCFR---------------PGTILHEFMHALG---FY 165

  Fly   914 HLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGISTGCVGRCESNPCLNNGTCI 978
            |..|..:       ||.::..|...::.||..:.::|:...:.....|
  Fly   166 HQQSSSI-------RDDFINVIYENIVPGKEFNFQKYADTVVTDFEVG----------------- 206

  Fly   979 ERYDGYSC-DCRWSAFKGPICADEIGVNLRSSSII 1012
              ||..|| ..|..||.  |..::..|.|.||::|
  Fly   207 --YDYDSCLHYRPGAFS--INGEDTIVPLDSSAVI 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrx-IV	NP_524034.2	FA58C	46..185	CDD:214572
		FA58C	57..184	CDD:238014
		LamG	192..340	CDD:238058
		LamG	376..514	CDD:238058
		EGF	546..575	CDD:278437
		Laminin_G_2	824..943	CDD:280389	20/119 (17%)
		EGF_CA	966..998	CDD:238011	7/32 (22%)
		Laminin_G_2	1032..1156	CDD:280389
		4.1m	1239..1255	CDD:128590
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	48/230 (21%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	48/230 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930