DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3l and AT5G25757

DIOPT Version :9

Sequence 1:	NP_648553.1	Gene:	eIF3l / 39386	FlyBaseID:	FBgn0036258	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_680223.1	Gene:	AT5G25757 / 832644	AraportID:	AT5G25757	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	216/517 - (41%)
Similarity:	333/517 - (64%)	Gaps:	31/517 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EYERNYYAARMPDNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIV 92
            |.|..|....:||:||.|:.:..:.|::.|:|:|..|.|.:|..||:..|..|.||..:.:|..|
plant    13 ERESGYDPNMVPDSVKSFVSHMYRHIRDKNVYEIHQMCETSFQSISERLFKDTPWPSVEAIAPYV 77

  Fly    93 DNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELV 157
            |||.||.:||:|:::||::||:  .|.|:|||:|:.|||..|.:::  ...|.::||:.|||::|
plant    78 DNDHVFCLLYREMWFRHLYARL--SPTLKQRIDSYDNYCSLFQVVL--HGVVNMQLPNQWLWDMV 138

  Fly   158 DEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGV 222
            ||||||||:|.|:||:|..|:::|| .|...|...|::..:||.|.:||:.|.|.:.||....|:
plant   139 DEFVYQFQSFCQFRAKLKNKTEEEI-ALLRQHDKAWNVYGVLNFLQALVEKSCIIQILEHDKDGL 202

  Fly   223 D-PQTVAGDF-GKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQIS 285
            : .:|...|| |..:..|:|||||:|||||||.|||||:.|:|.|:||:|.:...|:.:..|.|:
plant   203 EFTETDGYDFSGGSNVLKVLGYFSMVGLLRVHCLLGDYHTALKWLQPIDITQPGVYTSVIGCHIA 267

  Fly   286 TSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHP 350
            |.|:.|||.:|:|||.||:|.|:.|||||.:||| |..:|.|.:|:.|:.||||.|||:.|.|.|
plant   268 TIYHYGFATLMLRRYVDAVREFNKILLYIFKTKQ-YHQKSPQYEQLLKKNEQMYALLALSLSLCP 331

  Fly   351 Q--CIDESIQQVLREKNYHDAMFKMQCGDLE---VFKSFFVFACPRFVSP-CPPAVDAPMDDYVK 409
            |  .:|||:...||:| |.:.|.:|...|.|   ::...|.:|||:|::| .||..:.|:.:|.:
plant   332 QTKLVDESVNSQLRDK-YGEKMMRMLRSDDEAFGIYDELFSYACPKFITPSAPPTFEEPLVNYNQ 395

  Fly   410 DPMEHQLQVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKM 474
            |....||::|:.||:||:.|...|::||:|:::.|.|||:::     |.|...|...||.:|||.
plant   396 DAYRLQLKMFLYEVKQQQLLSGVRTFLKVYSSISLAKLANYM-----EVDEPTLRTILLTYKHKT 455

  Fly   475 RNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILK----FNDLNR 532
            .::       ..:|...|.:::||:|::|||::.::|.:.||||||:|:|.|    .||::|
plant   456 HSV-------DSDGRIISNADIDFFINNDMIYVVESKPAKRYGDFFLRQIAKLEGVINDMDR 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:287257	176/416 (42%)
AT5G25757	NP_680223.1	Paf67	105..501	CDD:402046	175/412 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	311	1.000	Domainoid score	I308
eggNOG	1	0.900	-	-		E1_KOG3677
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9380
Inparanoid	1	1.050	388	1.000	Inparanoid score	I510
OMA	1	1.010	-	-		QHG53715
OrthoDB	1	1.010	-	-		D393910at2759
OrthoFinder	1	1.000	-	-		FOG0006510
OrthoInspector	1	1.000	-	-		oto3227
orthoMCL	1	0.900	-	-		OOG6_102359
Panther	1	1.100	-	-	LDO	PTHR13242
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4745
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840