Protein Alignment eIF3l and eif3s6ip

DIOPT Version :10

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_998293.1
• Gene: eif3s6ip / 406402
• ZFINID: ZDB-GENE-040426-2138
• Length: 576
• Species: Danio rerio
• Alignment Length: 557
• Identity: 302/557 - (54%)
• Similarity: 402/557 - (72%)
• Gaps: 34/557 - (6%)

  Fly     5 DEYATNSDYYDDYAHTGDPQLDMEYERNYYAAR----MPDNVKYFLINFCQAIK----------- 54
            |.|:..:||  || |||||:.|:.|||.|...:    :|:.:|.||..|.:.|.
Zfish    13 DPYSYPNDY--DY-HTGDPKADLAYERQYEHQQTYHVIPEVIKNFLQYFHKTISDLIDQKVYELQ 74

  Fly    55 ---------EGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHI 110
                     |..:|:||::|||::.:::|..|..:.|||.:.:|::|.||.||||||||||||||
Zfish    75 ANRVSSESIEQKIYEIQDVYENSWNKLTDRFFKTSPWPEAEAIASLVGNDAVFLILYKELYYRHI 139

  Fly   111 HARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLT 175
            :|::.|||.|:||..|::|||:.||.|::|..|..||||:.|||:::|||:||||:|:|||.:..
Zfish   140 YAKVSGGPTLDQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTA 204

  Fly   176 EKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKML 240
            :||::||:.| .|:...|::..:|||||||||.|||.:|||..:.|.||::|||::|:.|.||||
Zfish   205 KKSEEEIEFL-RNNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKML 268

  Fly   241 GYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIR 305
            ||||||||||:|||||||||||||||.||::|||.||.:|.|||:|.|||||||:|||||.||||
Zfish   269 GYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQITTYYYVGFAYLMMRRYQDAIR 333

  Fly   306 TFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAM 370
            .|::||||||||:.::...:|:.:.||||.|||:.||||.|.::|..|||||...|||| |.|.|
Zfish   334 VFANILLYIQRTRNMFQRTTYKYEMINKQNEQMHGLLAIALTMYPMRIDESIHTQLREK-YGDKM 397

  Fly   371 FKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQKDLPTTRSY 435
            .:||.|||:||:..|.||||:|:||..|..:....:|.|:|.:.||:||.:||:||..|.|.||:
Zfish   398 LRMQKGDLQVFEELFSFACPKFLSPVVPNYENVHPNYHKEPFQQQLKVFAEEVQQQAQLSTIRSF 462

  Fly   436 LKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYI 500
            ||||||:|:.|||.|:|.:..|     ..|:||.|||||:||||:.|.|.|:|.|:|.||:||||
Zfish   463 LKLYTTMPVAKLAGFLDMSEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYI 522

  Fly   501 DDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNI 537
            |.||||||||||:.||||||:|:|.||.:|||.||.:
Zfish   523 DKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKM 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:463028	238/404 (59%)
eif3s6ip	NP_998293.1	Paf67	151..549	CDD:463028	238/404 (59%)