Protein Alignment eIF3l and eif3l

DIOPT Version :9

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_988980.1
• Gene: eif3l / 394577
• XenbaseID: XB-GENE-493733
• Length: 562
• Species: Xenopus tropicalis
• Alignment Length: 567
• Identity: 299/567 - (52%)
• Similarity: 401/567 - (70%)
• Gaps: 40/567 - (7%)

  Fly     2 YGGDEYATNSDYYD---DY-AHTGDPQLDMEYERNY----YAARMPDNVKYFLINFCQAIK---- 54
            |..:|:..:.|.|:   || .|||||:.|:.|||.|    |.. :|:.:|.|:..|.:.:.
 Frog     3 YANEEFEGSYDPYNYQADYDMHTGDPKQDLAYERQYEQQTYQV-IPEVIKNFIQYFHKTVSDLID 66

  Fly    55 ----------------EGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYK 103
                            :..:|:||::|||::.::::..|..:.|||.:.:|..|.||.|||||||
 Frog    67 QKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNSPWPEAEAIAPQVGNDAVFLILYK 131

  Fly   104 ELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFA 168
            |||||||:|::.|||.||||..|::|||:.||.|::|..|..||||:.|||:::|||:||||:|:
 Frog   132 ELYYRHIYAKVSGGPTLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFS 196

  Fly   169 QYRARLTEKSQDEIQQLCVNHSNE--WSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDF 231
            |||.:..:||::||:.|   .||.  |::..:|||||||||.|||.:|||..:.|.||::|||::
 Frog   197 QYRCKTAKKSEEEIEFL---RSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEY 258

  Fly   232 GKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMM 296
            |:.|.||||||||||||||:|||||||||||||||.||::|||.||.:|.||::|.|||||||:|
 Frog   259 GRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLM 323

  Fly   297 MRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVL 361
            ||||.||||.|::|||||||||.::...:|:.:.||||.|||:.||||.|.::|..|||||...|
 Frog   324 MRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHGLLAIALTMYPMRIDESIHTQL 388

  Fly   362 REKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQ 426
            ||| |.|.|.:||.||.::::..|.:|||:|:||..|..|....:|.|:|...||:||:|||:||
 Frog   389 REK-YGDKMLRMQKGDAQIYEELFNYACPKFLSPVVPNYDNVHPNYHKEPYLQQLKVFLDEVQQQ 452

  Fly   427 KDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFK 491
            ..|.|.||:||||||:|:.|||.|:|....|     ..|:||.|||||:||||:.|.|.|||.|:
 Frog   453 AQLSTIRSFLKLYTTMPVAKLAGFLDLPEQE-----FRIQLLVFKHKMKNLVWTSGISALEGEFQ 512

  Fly   492 SGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNIN 538
            |.||:|||||.||||||||||:.||||||:|:|.||.:||:.||.::
 Frog   513 SASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNKTLKKMS 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:287257	238/406 (59%)
eif3l	NP_988980.1	Paf67	153..548	CDD:370925	236/403 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	486	1.000	Domainoid score	I391
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9380
Inparanoid	1	1.050	589	1.000	Inparanoid score	I977
OMA	1	1.010	-	-		QHG53715
OrthoDB	1	1.010	-	-		D393910at2759
OrthoFinder	1	1.000	-	-		FOG0006510
OrthoInspector	1	1.000	-	-		oto102369
Panther	1	1.100	-	-	LDO	PTHR13242
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2511
SonicParanoid	1	1.000	-	-		X4745
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110