Protein Alignment eIF3l and Eif3l

DIOPT Version :10

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_660121.2
• Gene: Eif3l / 223691
• MGIID: 2386251
• Length: 564
• Species: Mus musculus
• Alignment Length: 567
• Identity: 300/567 - (52%)
• Similarity: 396/567 - (69%)
• Gaps: 40/567 - (7%)

  Fly     2 YGGDEYATNSDYYDDYA-------HTGDPQLDMEYERNY----YAARMPDNVKYFLINFCQAIK- 54
            |..|:|.:.: .||.||       |||||:.|:.|||.|    |.. :|:.:|.|:..|.:.:.
Mouse     3 YPADDYESEA-AYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQV-IPEVIKNFIQYFHKTVSD 65

  Fly    55 -------------------EGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLI 100
                               :..:|:||::|||::.::::..|..|.|||.:.:|..|.||.||||
Mouse    66 LIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLI 130

  Fly   101 LYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQ 165
            ||||||||||:|::.|||.||||..|::|||:.||.|::|..|..||||:.|||:::|||:||||
Mouse   131 LYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQ 195

  Fly   166 NFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGD 230
            :|:|||.:..:||:.|:..|..| ...|::..:|||||||||.|||.:|||..:.|.||::|||:
Mouse   196 SFSQYRCKTAKKSEGEMDFLRSN-PKVWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGE 259

  Fly   231 FGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYM 295
            :|:.|.||||||||||||||:|||||||||||||||.||::|||.||.:|.||::|.|||||||:
Mouse   260 YGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYL 324

  Fly   296 MMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQV 360
            |||||.||||.|::|||||||||.::...:|:.:.||||.|||:.||||.|.::|..|||||...
Mouse   325 MMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQ 389

  Fly   361 LREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQ 425
            |||| |.|.|.:||.||.:|::..|.:|||:|:||..|..|....:|.|:|...||:||.|||:|
Mouse   390 LREK-YGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQ 453

  Fly   426 QKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTF 490
            |..|.|.||:||||||:|:.|||.|:|....|     ..|:||.|||||:||||:.|.|.|:|.|
Mouse   454 QAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQE-----FRIQLLVFKHKMKNLVWTSGISALDGEF 513

  Fly   491 KSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNI 537
            :|.||:|||||.||||||||||:.||||||:|:|.||.:|||.||.:
Mouse   514 QSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKM 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:463028	236/404 (58%)
Eif3l	NP_660121.2	Paf67	152..550	CDD:463028	236/404 (58%)