Protein Alignment eIF3l and C03H5.5

DIOPT Version :10

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_493721.2
• Gene: C03H5.5 / 182182
• WormBaseID: WBGene00015407
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 119/539 - (22%)
• Similarity: 209/539 - (38%)
• Gaps: 128/539 - (23%)

  Fly    40 DNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEV-AAIVDNDKVFLILYK 103
            |.|..:|.:|.:.|.|.||.:|||.|.:....:.........||:|..| .:|...::.|::|||
 Worm    96 DIVLEYLAHFSKMIAENNLLEIQNCYYDRLETVQKQLPPSFTWPDEITVRKSISPENQDFMVLYK 160

  Fly   104 ELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFA 168
            ||.||.::|      :..|..:...||...|:::     |..|.|||.|:.::::|:|:|.|...
 Worm   161 ELKYRRLNA------EARQNKDMLENYQSIFSIL-----PGKLNLPDYWILDIMEEYVFQIQTSI 214

  Fly   169 QYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGK 233
            .....::.|.                  ..||.|.||.      .|.||
 Worm   215 ISTESVSNKD------------------AALNTLISLA------SQPEA---------------- 239

  Fly   234 LSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLE--PIEIHKKSAYSHIPACQISTSYYVGFAYMM 296
                 .|...||:||:|:|..|.|:....::|:  |.||.....       .|..:|.:||||::
 Worm   240 -----NLKTLSLLGLIRMHIFLQDHQSTSQILDQMPPEIQGTET-------MIRVTYQIGFAYLI 292

  Fly   297 MRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQV- 360
            :.|:|:::..|..:|                 ....:|||: :.:.|:..:.:  ||..|.:::
 Worm   293 IGRFAESVDRFLKVL-----------------SSSVEQAEK-FKINALPCIAY--CISNSSKELE 337

  Fly   361 -------LREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQV 418
                   ..|..|.:.|...:...:|.|.|||. .|..|:...|.  :..:..:.|......:..
 Worm   338 IPSEISKHVESTYPNQMKDWKEAKIETFLSFFA-ECSSFIPQLPR--NNKLSLHWKSQNLKSMVF 399

  Fly   419 FMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDV------SKLLIRLLCFKHKMRNL 477
            ::..|...|.|...:..||:...|||...|:.:.|.::..|:      ...|.||:..|......
 Worm   400 YLQRVTTWKPLRNLKGLLKICPVLPLEARATSLLPVSTSSDIDYFCQYDSFLNRLVTVKPSKLTK 464

  Fly   478 VWSKGPSG---------------LEGTFKSGSELDFYIDD---DMIHI-----ADTKVSHRYGDF 519
            ::...|..               :..|.:..:::|..|.|   ..|.:     .:.|:.......
 Worm   465 IFQDFPDANRQKTLVFLIMKYHKILQTVQKSAKIDEKIADFGRKFIGVLGKAHKNLKIDQEDAMC 529

  Fly   520 FVRKILK--FNDLNRKLKN 536
            ::|::.|  .:|.||.::|
 Worm   530 YMREVAKISMDDANRFVEN 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:463028	89/445 (20%)
C03H5.5	NP_493721.2	Paf67	179..>307	CDD:463028	44/184 (24%)