Protein Alignment RhoGAP68F and ECM25

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_012334.1
• Gene: ECM25 / 853229
• SGDID: S000003737
• Length: 599
• Species: Saccharomyces cerevisiae
• Alignment Length: 319
• Identity: 62/319 - (19%)
• Similarity: 132/319 - (41%)
• Gaps: 76/319 - (23%)

  Fly   155 YILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFS-----PFIS 214
            |.||.|..|..: .|.|..:....:.:|.:..:..|:.:::||.::|:|.::...|     .|:.
Yeast    64 YSLVIFSSGFSQ-RKISWVYGIKMFAKLPKETKFYLQKIFIVHESFFVRSVYQVISNAMNFNFLD 127

  Fly   215 DKFRK----KLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQH 275
            .|..:    .||::..|..|.:.:.:.:|::..|:...|.::.           .:||...:..:
Yeast   128 SKDSQHDFPSLVHVLDLTSLSELIDITRLRISLNVYLYDYQIR-----------EHINVPEEYYN 181

  Fly   276 KMATTHQFGVPL-----KFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMAL 335
            ::       .||     :.:|.:.        |.:|..:...:     .|.||::.||:.::...
Yeast   182 RL-------TPLAIRQYRQLVFDK--------IFKKLQNDALL-----CELIFQKPGNYKKVNIF 226

  Fly   336 KERVNRGEDVDLKSVNVHVIAGL-LKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIR 399
            .:.:.|...:||...:::.:|.: |..|:::.|:||:..||       :..|..:..:..::..|
Yeast   227 LDIIKRNNYIDLSQWDIYSLASVWLNYFIKNKAKPLIPIEL-------IPLPIVDDLKFTSETFR 284

  Fly   400 EKLPEENY-ELFKYIVEFLVRVMD--------------------C-EDLNKMTSSNLAI 436
            :.:....| :||..|:.|..|::.                    | |.|:.||:..|||
Yeast   285 KIIKFNQYQDLFMVIIPFFNRIIAHGESTKHDSRTLSKALTPALCKEKLSMMTNDRLAI 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	21/95 (22%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	37/187 (20%)
ECM25	NP_012334.1	CRAL_TRIO_2	21..167	CDD:463965	22/103 (21%)
		RhoGAP	190..359	CDD:214618	35/174 (20%)
		Herpes_BLLF1	<376..>519	CDD:282904