Protein Alignment RhoGAP68F and ARHGAP9

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_047285285.1
• Gene: ARHGAP9 / 64333
• HGNCID: 14130
• Length: 798
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 75/289 - (25%)
• Similarity: 126/289 - (43%)
• Gaps: 52/289 - (17%)

  Fly   214 SDKFRKKLVYISS-LDELRQALGL------NKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASR 271
            |:...|.|:.:|| ...:|...|.      ||||               |..:..||..::
Human   532 SELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLK---------------RLIAKRPPLQSL---- 577

  Fly   272 QQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALK 336
             |:..:.....||..|:.:.....  :::|..:|.|:.::...| :|.:||:|.|||.:.:..|:
Human   578 -QERGLLRDQVFGCQLESLCQREG--DTVPSFLRLCIAAVDKRG-LDVDGIYRVSGNLAVVQKLR 638

  Fly   337 ERVNR----------------GED--VDLKSV---NVHVIAGLLKSFLRDLAEPLLTFELYEDVT 380
            ..|:|                |::  :||.|.   ::||:.|.||.|||:|.:||:...|.....
Human   639 FLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR 703

  Fly   381 GFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPN-FLW 444
            ..|...:.|:..:..|.:...:|:.|::..:|::|.|.||:...|.|:||..||.|||||. |..
Human   704 AALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP 768

  Fly   445 SRSTSTSLEEIAPINAFVDFVLQNHKDIY 473
            .:.||............|..:|.|...::
Human   769 EQETSDPAAHALYPGQLVQLMLTNFTSLF 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	11/34 (32%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	60/216 (28%)
ARHGAP9	XP_047285285.1	SH3_ARHGAP9	74..130	CDD:213019
		PHA03377	<170..>360	CDD:177614
		PH_ARHGAP9-like	372..484	CDD:270053
		RhoGAP_ARHGAP27_15_12_9	588..792	CDD:239868	59/206 (29%)