Protein Alignment RhoGAP68F and RhoGAP68F

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_061500543.1
• Gene: RhoGAP68F / 5666852
• VectorBaseID: AGAMI1_000143
• Length: 497
• Species: Anopheles gambiae
• Alignment Length: 471
• Identity: 257/471 - (54%)
• Similarity: 346/471 - (73%)
• Gaps: 14/471 - (2%)

  Fly    23 PAINPIVDNSDEPQPSLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFV-LAEDPELEPEEDV- 85
            |...|::|::::|.|||||.||:||.||||||||..|||......|.|.: .:.:.|:..|:::
Mosquito    22 PLNPPMIDSTEDPHPSLSDWHDYEPNLEFDDTELTHPSPEPGTTTVFDDINYSAEFEIPSEDEII 86

  Fly    86 -NPLE-DDFEDQLR-----EQSENFQTPRNK-CDFLGTDKQGRHIFGIYASRFPEKSQLEG--FV 140
             ..|| |::|:||.     |.:......|.| .:|:||||||:.|..|||.|.||:..|..  |:
Mosquito    87 KTTLEADNYEEQLTMVGHDENAIRKDFKRRKFIEFIGTDKQGQPIIAIYACRLPERKDLNSNIFI 151

  Fly   141 REIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVI 205
            ..|||.:|.||:||||:.|||||:|::|||:.||||||||||||:|:||||.|||||.|.|||::
Mosquito   152 DFIIKSMEEFVQNDYIIAYFHQGMKDNNKPALQFLWNSYKELDRSFKKNLKKLYVVHSTTFIRMV 216

  Fly   206 WNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINAS 270
            |.||.|.||:||:.||:|.||||||:|:||||.||:||.:.:.|:|:|...:.:.....|::.:|
Mosquito   217 WFFFKPIISEKFKSKLIYTSSLDELKQSLGLNTLKVPDPVKEFDEKINNGTRYTLRGSKSSLKSS 281

  Fly   271 RQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMAL 335
            |..:: :..:.||||.|:||:.||.|||.||||||||||.||:..|::||||||||||::.|..|
Mosquito   282 RSLEN-LPKSAQFGVSLRFIIENSACLNCIPPIVRKCVDHLSLPDVVETEGIFRRSGNYARIKEL 345

  Fly   336 KERVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEE-RSRNVTQLIR 399
            :.::|.|::|.|.:.:.||:|.|||:|||:|.|||||:|||||:|.|.:|..|| |||||.||:|
Mosquito   346 RAKINAGDEVQLSNEDTHVVASLLKTFLRELEEPLLTYELYEDITQFGEWKTEETRSRNVKQLLR 410

  Fly   400 EKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDF 464
            |:||||||||||||||||.::|:.:|.|||||||||||||||.:|.:....||:||.|||||:|:
Mosquito   411 ERLPEENYELFKYIVEFLGKIMERKDFNKMTSSNLAIVFGPNLIWPKQEQMSLDEIGPINAFIDY 475

  Fly   465 VLQNHKDIYLIDVNQR 480
            |||:..|||.:|:|::
Mosquito   476 VLQHQDDIYFVDINKK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	79/124 (64%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	123/195 (63%)
RhoGAP68F	XP_061500543.1	None