Protein Alignment RhoGAP68F and arhgap8

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001016951.1
• Gene: arhgap8 / 549705
• XenbaseID: XB-GENE-6455435
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 439
• Identity: 159/439 - (36%)
• Similarity: 235/439 - (53%)
• Gaps: 52/439 - (11%)

  Fly    53 DTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSE------NFQTPRNK-C 110
            |.|.||...|:||                |||:..|........|:.|:      .:...|:. .
 Frog     5 DFEKLAEIELQKD----------------EEDLEYLGPPVVSGGRKPSDVCIGHPYYDIARHGIL 53

  Fly   111 DFLGTDKQGRHIFGIYASRFPEKSQLEGFVR--EIIKE-IEPFVENDYILVYFHQGLKEDNKPSA 172
            ..:|.|..||.:......|.|...::: .||  :.:|. ::.:|||||.|||||.||...||||.
 Frog    54 HVVGDDNSGRKVITFSCCRLPPCHEID-HVRLLQYMKHTLDQYVENDYTLVYFHYGLNSRNKPSL 117

  Fly   173 QFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLN 237
            .:|.::|||.||.::||||.|||||||.||:|:||.|.|.||.||.||::|:..|:||.:.|..|
 Frog   118 GWLQSAYKEFDRKYKKNLKALYVVHPTNFIKVLWNIFKPIISHKFGKKVLYMKDLNELHEHLKFN 182

  Fly   238 KLKLPDNICDLDDKLNPSR-KPS---TPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLN 298
            :|.:|..:...|:||...: |||   :|||...:           .|.||||.|::| .|....:
 Frog   183 RLIIPPEVLQHDEKLRAHKGKPSSAKSPPPRPPL-----------PTQQFGVTLQYI-RNKNNGD 235

  Fly   299 SIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSF 362
            .|||::.:.:..|...| :.|||:||||.:...:..:::..|.|:.|:..:. |:|:.|.:||:|
 Frog   236 LIPPVMVQTISYLKQKG-LRTEGLFRRSVSVHILKDVQKLYNVGKPVNFDTYDNIHIPAVILKTF 299

  Fly   363 LRDLAEPLLTFELY---EDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCE 424
            ||:|.|||||::.|   :|:.|.....:..|.|.:.|    ||||.||.:.||::.||..|....
 Frog   300 LRELPEPLLTYDSYGPIQDIIGVESSLRVTRCRQIVQ----KLPEHNYAVLKYLLCFLHLVCQQH 360

  Fly   425 DLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIY 473
            ..||||||||..:||.|.:|.|....||..:.|:|.|.:.:::.:..|:
 Frog   361 IHNKMTSSNLGCIFGLNLIWQREQIQSLNALVPVNLFAELLIEFYPQIF 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	60/125 (48%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	72/198 (36%)
arhgap8	NP_001016951.1	CRAL_TRIO_2	62..195	CDD:463965	61/133 (46%)
		RhoGAP	218..409	CDD:470621	72/196 (37%)