Protein Alignment RhoGAP68F and arhgap1

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001008141.1
• Gene: arhgap1 / 493503
• XenbaseID: XB-GENE-1015089
• Length: 435
• Species: Xenopus tropicalis
• Alignment Length: 463
• Identity: 152/463 - (32%)
• Similarity: 239/463 - (51%)
• Gaps: 66/463 - (14%)

  Fly    39 LSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENF 103
            ||||:|   .|:.|:|..|                 :..:|...:|.|...||.:|.....:::.
 Frog     6 LSDLND---DLDKDETNQL-----------------DQLKLASLDDKNWPSDDVQDYPNNANDSK 50

  Fly   104 QTP-----------------RNKCDFLGTDKQGRHIFGIYASRFPEKSQLE--GFVREIIKEIEP 149
            .:|                 |...:..|.||.||.|....|.|.|...:::  ..::.:...::.
 Frog    51 PSPDPVTHLRWDDPYYDIAWRQIVEVAGDDKYGRKIVVFSACRLPPCHEIDHVKLLQYLKHTLDQ 115

  Fly   150 FVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFIS 214
            :||:||.|||.|.||..:||||..:|.::|:|.||.::||:|.||:||||.||:.:...|.|.||
 Frog   116 YVESDYTLVYLHHGLTSENKPSLGWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIIS 180

  Fly   215 DKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLN-------PSRKPSTP-PPSSNINASR 271
            .||.:|:.|.:.|.:|.:.:.:.:|.:|..:...||.:.       .::||..| ||..|
 Frog   181 FKFGRKIFYANYLSDLEEHMKVEQLGIPKQVLKYDDLIRSNLKTSAATQKPGPPRPPLPN----- 240

  Fly   272 QQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALK 336
                     .|||:.|..:....|..:.||.:||..|..|. ...:.||||||||.....:..::
 Frog   241 ---------QQFGISLLHLKEKHPENDKIPLVVRDTVAFLQ-ENALSTEGIFRRSARTQIVREVQ 295

  Fly   337 ERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIRE 400
            ::.|.|..|..:.. :||:.|.:||:|||:|.|||||:.||..|   :|:.|:|:....|..|.:
 Frog   296 QKYNMGVQVTFQQYDDVHLPAVILKTFLRELPEPLLTYNLYSFV---VDFSKQEQKIESTLQILQ 357

  Fly   401 KLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFV 465
            .||:|||::.:::..|||.|....:.||||::|||:|||||.||.:..:.:|:.|.|||.|..|:
 Frog   358 TLPKENYDVLQFLTAFLVEVSSHNEQNKMTTTNLAVVFGPNLLWVKDAAMTLKAINPINTFTKFL 422

  Fly   466 LQNHKDIY 473
            |.|.::::
 Frog   423 LDNQRELF 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	47/124 (38%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	76/195 (39%)
arhgap1	NP_001008141.1	CRAL_TRIO_2	83..216	CDD:463965	48/132 (36%)
		RhoGAP-p50rhoGAP	240..430	CDD:239869	77/207 (37%)