Protein Alignment RhoGAP68F and RhoGAP18B

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 110/523 - (21%)
• Similarity: 187/523 - (35%)
• Gaps: 157/523 - (30%)

  Fly     4 HSRFAPRL----PVIVCQL-YRNRPAINPIVDNSD---EPQPSLSDLHDFEPKLEFDDTELLAPS 60
            |.||..|:    |....|| ..|..::.|..|:|.   |.:.|.:..|:..|.:         |.
  Fly   907 HQRFMTRIRRPAPPPPAQLATSNTTSLAPRSDDSGCSCEAEDSYNHQHNPTPAI---------PK 962

  Fly    61 PLEKD--------------------------------VMVGDFVLAEDPELEPEEDVNPLEDDFE 93
            ||:::                                :::.|.|||....|   :|||..||: |
  Fly   963 PLKEEWERAVLAAGAVAGKRGVAPRTGRKLRVRSNARLLLTDSVLAWRETL---QDVNCCEDE-E 1023

  Fly    94 DQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILV 158
            |.:        .|                                 |.:|::.
  Fly  1024 DMI--------VP---------------------------------VTDILRA------------ 1035

  Fly   159 YFHQGLKEDN---KPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKK 220
               |.::|||   :.....:...||.:...   ||..|                 |...||...|
  Fly  1036 ---QQIQEDNEVQQTQQSTILQRYKSVSIG---NLLDL-----------------PGEDDKKSIK 1077

  Fly   221 LVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGV 285
                   :.:|....:|......|.....:|.:.||:       ..:|:....:.|...   |..
  Fly  1078 -------NRMRMKFAVNSNVFRINRSPKSEKKSRSRR-------GQVNSLYLDEQKYPL---FAA 1125

  Fly   286 PLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVD-LKS 349
            ||..:.:|.....::|..|......:.....|:.:|::|.|||...:..|::::....|.. ||:
  Fly  1126 PLSALELNMTDHPNVPRFVVDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKLTHVYDPRWLKT 1190

  Fly   350 VNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIV 414
            .::|.:..|.|.|.|:|..||:|.|.||.:...|:   ::.:.....|..:.:||.|....::::
  Fly  1191 DDIHTLTSLHKQFFRELTSPLITQEAYERLGRSLN---DDAAIERMSLAFDDMPEPNRSTLRFLI 1252

  Fly   415 EFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQ 479
            ..|.||......|:|.|:|||||:||..|   |.:....:|..:|.....:::|:..|:..| |:
  Fly  1253 RHLTRVAAASASNRMPSTNLAIVWGPCLL---SANQIQLDIGRMNMLAKVLIENYDRIFHPD-NE 1313

  Fly   480 RTV 482
            |.|
  Fly  1314 RLV 1316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	17/125 (14%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	51/195 (26%)
RhoGAP18B	NP_573352.2	RhoGAP	1141..1285	CDD:459875	44/149 (30%)