Protein Alignment RhoGAP68F and Arhgap22

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_038950392.1
• Gene: Arhgap22 / 306279
• RGDID: 1307237
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 220
• Identity: 66/220 - (30%)
• Similarity: 104/220 - (47%)
• Gaps: 25/220 - (11%)

  Fly   262 PPSSNINASRQQQHKMATTH---QFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIF 323
            |.|:.|...|.:.    |.|   :||..|            .|.:|.:|||.:...| :..||:|
  Rat   169 PLSTGIFGQRLED----TVHHERKFGPRL------------APLLVEQCVDFIRERG-LSEEGLF 216

  Fly   324 RRSGNHSEIMALKERVNRGEDVDLKS-VNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPK 387
            |..|..:.:..|::..:.||.....| .:||.:|.|||.:||:|.||::.|..|||.........
  Rat   217 RMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVIPFARYEDFLSCAQLLT 281

  Fly   388 EERSRNVTQLIRE--KLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR--ST 448
            ::......:|.::  .||:.||.|.:||..||..|....|:|||:..|||.|||||.|..:  ..
  Rat   282 KDEGEGTVELAKQVSNLPQANYNLLRYICRFLDEVQAHSDVNKMSVQNLATVFGPNILRPQVEDP 346

  Fly   449 STSLEEIAPINAFVDFVLQNHKDIY 473
            .|.:|..:.:...:..:::.|..::
  Rat   347 VTIMEGTSLVQHLMTVLIRKHGQLF 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965
		RhoGAP-p50rhoGAP	278..473	CDD:239869	62/202 (31%)
Arhgap22	XP_038950392.1	PH-like	42..157	CDD:473070
		RhoGAP_ARHGAP22_24_25	173..371	CDD:239855	64/214 (30%)
		DUF4670	<388..>703	CDD:464815
		SMC_prok_B	<614..>704	CDD:274008