Protein Alignment RhoGAP68F and Arhgap8

DIOPT Version :9

• Sequence 1: NP_001261744.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001004242.1
• Gene: Arhgap8 / 300115
• RGDID: 1303143
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 144/366 - (39%)
• Similarity: 205/366 - (56%)
• Gaps: 17/366 - (4%)

  Fly   105 GTDKQGRHIFGIYASRFPEKSQL--EGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLW 167
            |.|:|||.||.....|.|...||  :..:..:...::..|||||.:||||.||...||||..:|.
  Rat    27 GDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQHVENDYTIVYFHYGLSSQNKPSLGWLQ 91

  Fly   168 NSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKL 232
            |:|||.||.::||||.|||||||..|:.:||.|.|.||.||.||:.|.|:|.|||:.|..::|.:
  Rat    92 NAYKEFDRKYKKNLKALYVVHPTSLIKALWNIFKPLISHKFGKKVTYCSNLRELREHLQCDQLLI 156

  Fly   233 PDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFI-VMNSPCLNSIPPIVR 296
            |..:...|:||....|..|.||:..     ........|.||||.|::: ..|...|  |||::|
  Rat   157 PPEVVRYDEKLRNLHKGQTAPPTKT-----PPPRPPLPTQQFGVSLQYLRDKNQGEL--IPPVLR 214

  Fly   297 KCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEP 360
            ..|..|...| :.|||:||||.:...:..::...::|:.|:.... ::|:.|.:||:|||:|.:|
  Rat   215 WTVTYLREKG-LHTEGLFRRSASAQTVRQVQRLYDQGKPVNFDDYGDMHLPAVILKTFLRELPQP 278

  Fly   361 LLTFELYEDVTGFLDWPKEERSRNVT--QLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSS 423
            ||||:.||.:.|.   ...|.|..||  :||...|||.||.:.:|::.||..|......|||.||
  Rat   279 LLTFQAYEQILGI---TSVESSLRVTHCRLILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSS 340

  Fly   424 NLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIY 464
            |||.|||.|.:|......||..:.|:|.|.:.:::.:..::
  Rat   341 NLACVFGLNLIWPSQGVASLSALVPLNLFTELLIEYYDKVF 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001261744.1	SEC14	105..233	CDD:238099	63/129 (49%)
		RhoGAP-p50rhoGAP	269..464	CDD:239869	73/198 (37%)
Arhgap8	NP_001004242.1	SEC14	12..157	CDD:238099	63/129 (49%)
		RhoGAP	191..381	CDD:413382	72/195 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5448
eggNOG	1	0.900	-	-		E1_KOG4406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3085
OMA	1	1.010	-	-		QHG52084
OrthoDB	1	1.010	-	-		D1511935at2759
OrthoFinder	1	1.000	-	-		FOG0002972
OrthoInspector	1	1.000	-	-		otm45034
orthoMCL	1	0.900	-	-		OOG6_103505
Panther	1	1.100	-	-	O	PTHR45808
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3319
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840