Protein Alignment RhoGAP68F and Prune2

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001406496.1
• Gene: Prune2 / 293823
• RGDID: 1311350
• Length: 3080
• Species: Rattus norvegicus
• Alignment Length: 284
• Identity: 73/284 - (25%)
• Similarity: 121/284 - (42%)
• Gaps: 72/284 - (25%)

  Fly    30 DNSDEPQPSLSDLHDFEPKLEFDDTELLAPS-PLEKDVMVGDFVLAEDPELEPEE-DVNPLEDDF 92
            |...||..|| ||:...|:    ..:|.||: .|..|...|. :|::|....|:| |:|..|.|.
  Rat  2761 DMRPEPPNSL-DLNGSHPR----RIKLTAPNINLSLDQSEGS-ILSDDNLDSPDEIDINVDELDT 2819

  Fly    93 EDQLREQSENFQTPRN-------------------------------KCDFLGTDKQ-------- 118
            .|    ::::|:.|.:                               :...:|..:|
  Rat  2820 PD----EADSFEYPGHEDPMANRSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIE 2880

  Fly   119 --------------GRHIFGIYASRF-PEKSQ------LEGFVREIIKEIEPFVENDYILVYFHQ 162
                          |.:...::|:.| |:.|:      :|.....:|..:|..|..||::||.:.
  Rat  2881 PYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNG 2945

  Fly   163 GLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSL 227
            .......|...::...|:.:||..|||||:..:|||:||||.|.....||||.||..|:.|:|||
  Rat  2946 ATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSL 3010

  Fly   228 DELRQALGLNKLKLPDNICDLDDK 251
            .||...:.::.:.:|::|...|::
  Rat  3011 SELSGLIPMDCIHIPESIIKYDEE 3034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	43/129 (33%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869
Prune2	NP_001406496.1	DHHA2	214..>277	CDD:460719
		BNIP2	2778..2895	CDD:463609	19/125 (15%)
		CRAL_TRIO_2	2897..3034	CDD:463965	45/136 (33%)