Protein Alignment RhoGAP68F and rga6

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_595237.1
• Gene: rga6 / 2540304
• PomBaseID: SPBC354.13
• Length: 733
• Species: Schizosaccharomyces pombe
• Alignment Length: 551
• Identity: 114/551 - (20%)
• Similarity: 175/551 - (31%)
• Gaps: 200/551 - (36%)

  Fly    57 LAPSPL----------EKDVMVG-----DFVLAEDPELEPEEDVNPLEDDFEDQLREQSEN---- 102
            |.||.|          .|||::.     |....|:|.||....:..:|:.....:...:.|
pombe     3 LNPSTLNNGTLGDLKEHKDVVLSSNAQTDEKRFEEPSLEVGGSLAKVENGLSTSISSSASNLEGQ 67

  Fly   103 ---FQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQ--------LEGFVREIIKEIEPFVENDYI 156
               |.|.:|.|                .|||.|.:|        ||.:|.: |||::..:.:|..
pombe    68 QAPFFTKQNSC----------------LSRFRELAQTYNIHEINLEEYVSQ-IKEVKQSLYSDDS 115

  Fly   157 LVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWF-------------------- 201
            :  |::. |..:.|.|        ..|:.|........::|.|..
pombe   116 V--FNES-KSSSPPDA--------HTDKYFTPCGSPTKLIHSTLLEERDTPSSLEHVSFYLQESA 169

  Fly   202 ---IRVIWNFFSPFISDKFRKKLVYISSL----------------DELRQALGLNKLKLPDNICD 247
               :|    |..|..:....:..:.:|||                ::|..:..|..|:.|.:...
pombe   170 VSEVR----FDKPSNNGPLGRSSLNLSSLSHELQTSQDSPSLSATNQLSSSDTLEPLQYPPSSFG 230

  Fly   248 LDDKLN-----PSRKPSTPP-------PSSNINASRQQQ--HKMATT----------HQ------ 282
            ...:.|     |.|.||...       ||...:..||..  |:.:.|          ||
pombe   231 SQRQFNASQDSPKRSPSKGSWSSILRRPSLTYSPKRQSTGLHRRSLTNYFKFPHRNAHQHNAIAH 295

  Fly   283 ----FGVPL-----------KFIVMNSPCLNS---IPPIVRKCVDSLSITGVIDTEGIFRRSGNH 329
                ||.|:           ||......|...   :|.|..:||..||: ..:...||||.||:.
pombe   296 NPSVFGKPIGDLTSDPTNLCKFTFPTPECAPPSLLLPHIFAQCVHFLSL-NALHVPGIFRISGSG 359

  Fly   330 SEIMALKE------------------RVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELY 376
            ..|.|:.|                  |:.....:|        ||.:||.::..|...|.|   :
pombe   360 PVIKAITEYFYSPPHFWLDETSEIFKRIGFPSYID--------IAAVLKRYIMLLPGGLFT---H 413

  Fly   377 EDVTGFLDWPKEERSR-NVTQLIREKLPE------ENYELFKYIVEFL-------VRVMDCE--- 424
            :|:...|.....:.|| .|...||.::..      ::|..|..:...|       .|..:.|
pombe   414 KDILNLLVPLYVDSSRVKVPIDIRNEMAALCFSQIDSYVRFSILCSLLALLHQIATRTQELENGM 478

  Fly   425 ----DLNKMTSSNLAIVFGPNFLWSRSTSTS 451
                |...|....|.|:|||..|.:.||..|
pombe   479 ENTKDSTLMKPEALGIIFGPLLLGNSSTDLS 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	29/169 (17%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	56/247 (23%)
rga6	NP_595237.1	RhoGAP	331..528	CDD:214618	47/191 (25%)