Protein Alignment RhoGAP68F and Arhgap1

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001139374.1
• Gene: Arhgap1 / 228359
• MGIID: 2445003
• Length: 479
• Species: Mus musculus
• Alignment Length: 464
• Identity: 169/464 - (36%)
• Similarity: 253/464 - (54%)
• Gaps: 54/464 - (11%)

  Fly    35 PQPSLSDLHDFEPKLEFDDT-----ELLAPSPLEK----DVMVGDFVLAEDPELEPEEDVNPL-- 88
            |:.::..|.:.:..|..|||     :|...|..||    |.| .||..::|.:....|.|..|
Mouse    37 PERAMDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEM-PDFPKSDDSKSSSPEPVTHLKW 100

  Fly    89 EDDFEDQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLE-----GFVREIIKEIE 148
            :|.:.|..|.|.         .:..|.||.||.|....|.|.|...||:     |:::.   .::
Mouse   101 DDPYYDIARHQI---------VEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKH---TLD 153

  Fly   149 PFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFI 213
            .:||:||.|:|.|.||..|||||..:|.::|:|.||.::||:|.||:||||.||:.:...|.|.|
Mouse   154 QYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLI 218

  Fly   214 SDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSR-------KPSTP-PPSSNINAS 270
            |.||.:|:.|::.|.||.:.:.|.:|.:|..:...||.|..::       ||..| ||..|
Mouse   219 SFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPN---- 279

  Fly   271 RQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMAL 335
                      .||||.|:.:...||..:.||.::|:.|..|. ...:.||||||||.|...:..:
Mouse   280 ----------QQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQ-AHALTTEGIFRRSANTQVVREV 333

  Fly   336 KERVNRGEDVDLKSVN-VHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIR 399
            :::.|.|..||....| :|:.|.:||:|||:|.||||||:||..|.|||:..:.:|. .|||.:.
Mouse   334 QQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRV-EVTQQVL 397

  Fly   400 EKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDF 464
            :.||||||::..::..|||::....|.||||::|||:|||||.||::..:.:|:.|.|||.|..|
Mouse   398 QTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKF 462

  Fly   465 VLQNHKDIY 473
            :|.:..:::
Mouse   463 LLDHQGELF 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	52/127 (41%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	82/195 (42%)
Arhgap1	NP_001139374.1	CRAL_TRIO_2	122..256	CDD:463965	54/136 (40%)
		RhoGAP-p50rhoGAP	279..471	CDD:239869	83/207 (40%)