Protein Alignment RhoGAP68F and pac-1

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_498877.4
• Gene: pac-1 / 176201
• WormBaseID: WBGene00015418
• Length: 1605
• Species: Caenorhabditis elegans
• Alignment Length: 272
• Identity: 79/272 - (29%)
• Similarity: 120/272 - (44%)
• Gaps: 67/272 - (24%)

  Fly   247 DLDDKLNPSRKPSTPP------------------PSSNINASRQQQHKMATTHQFGVPLKFIVMN 293
            |:::...|:...:||.                  .|.:.:.|:||....|.....||.:......
 Worm   892 DIENGEAPTATATTPKSGRKWKKSKAAKQGSGGGSSGSSSGSQQQGAAGAPQPVLGVRIADCPTG 956

  Fly   294 SPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERV-NRGED-VDLKSV------ 350
            | |.:.:|.||:.||..:...| :||.||:|..||.:.:.||||.: |||.| |||..|
 Worm   957 S-CEDHVPMIVQACVCVIETYG-MDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPR 1019

  Fly   351 --NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPK----EERSRNVTQLIREKLPEENYEL 409
              :|:|::.|||.|||.|.|||||.:||   ..|:|..:    ..|...:..|:| |||..:|:.
 Worm  1020 WRDVNVVSSLLKMFLRKLPEPLLTDKLY---PFFIDANRISTHHNRLHKLRNLLR-KLPRPHYDT 1080

  Fly   410 FKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNF-----------------------------LWS 445
            .::::..|..:....|:|||...|||::|||:.                             ||.
 Worm  1081 LRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWM 1145

  Fly   446 RSTSTSLEEIAP 457
            ...|::.|:..|
 Worm  1146 FDESSTTEDAVP 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965
		RhoGAP-p50rhoGAP	278..473	CDD:239869	71/223 (32%)
pac-1	NP_498877.4	PH_ARHGAP21-like	613..728	CDD:269955
		RhoGAP_ARHGAP21	945..1146	CDD:239860	67/206 (33%)