DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP68F and BNIPL

DIOPT Version :10

Sequence 1:NP_001401037.1 Gene:RhoGAP68F / 39385 FlyBaseID:FBgn0036257 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_612122.2 Gene:BNIPL / 149428 HGNCID:16976 Length:357 Species:Homo sapiens


Alignment Length:233 Identity:61/233 - (26%)
Similarity:98/233 - (42%) Gaps:52/233 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 EDPELEPEEDVNPL----EDDFEDQLRE-----QSENFQTPRNKCDFLGTDKQGRH--IFG---- 124
            |..|||...|...|    |.::||:|..     .||..:.....|.:..|.:.|.|  :|.    
Human   122 EIDELETPSDSEQLDSGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPR 186

  Fly   125 ------------------------------IYASRFPEKSQ-------LEGFVREIIKEIEPFVE 152
                                          ::||.:..:|.       :|...|.::..:|..|.
Human   187 EQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVA 251

  Fly   153 NDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKF 217
            .:|:||:...|......|...::...|:.|||..||||:.|.|||.||:::.......||||.||
Human   252 ENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKF 316

  Fly   218 RKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPS 255
            .:|:.::.||.||.|.:.|:::.:|:.:..||..|:.|
Human   317 TRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLHGS 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP68FNP_001401037.1 CRAL_TRIO_2 119..242 CDD:463965 42/165 (25%)
RhoGAP-p50rhoGAP 278..473 CDD:239869
BNIPLNP_612122.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 32..156 10/33 (30%)
BNIP2 83..211 CDD:463609 17/88 (19%)
CRAL_TRIO_2 213..350 CDD:463965 42/136 (31%)
Blue background indicates that the domain is not in the aligned region.

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