Protein Alignment RhoGAP68F and sh3bp1

DIOPT Version :10

• Sequence 1: NP_001401037.1
• Gene: RhoGAP68F / 39385
• FlyBaseID: FBgn0036257
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_031756949.1
• Gene: sh3bp1 / 101733422
• XenbaseID: XB-GENE-984798
• Length: 636
• Species: Xenopus tropicalis
• Alignment Length: 450
• Identity: 113/450 - (25%)
• Similarity: 194/450 - (43%)
• Gaps: 108/450 - (24%)

  Fly    41 DLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENFQT 105
            ||.|||..||.|..:     ||.|               ..|||: |.......||::...::.|
 Frog   110 DLADFEISLERDVLQ-----PLAK---------------LSEEDL-PTILKHRKQLQKLITDWNT 153

  Fly   106 PRNKCDFLGTD---KQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKED 167
            .:::...:..:   .||....|..|.....|.:.:    |:.:::|. .:::||...::...||
 Frog   154 AKSRLSQIQKNINAGQGGGSTGTAAKLESLKEEED----ELRRKLEQ-SKDEYIADLYNYTTKE- 212

  Fly   168 NKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYIS-SLDELR 231
                        ||.:|.|.:.|:.....|                    :|.|.::: :|:||:
 Frog   213 ------------KECERYFIQLLELQAEYH--------------------KKSLSHLTDALEELK 245

  Fly   232 QALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPC 296
            .   |.|..:.|:|                              :.|:...:||||:..:....|
 Frog   246 D---LQKETVQDSI------------------------------EQASAEVYGVPLETHLAKFEC 277

  Fly   297 LNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV--NVHVIAGLL 359
            ..::|  :..||..|...| :..||:||.:...|.:..||..:..|.. ||.:.  ..|.:||.|
 Frog   278 EIAVP--ISACVRMLLAQG-MQEEGLFRLAAGASVLKKLKACLRAGAS-DLSNFMSEPHAVAGAL 338

  Fly   360 KSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCE 424
            ||:||:|.|||:|:||::|..........|:.....:...:|||..||...:|:::|:.::.:.:
 Frog   339 KSYLRELPEPLMTYELFDDWMTCASTKDPEKRLECYRDACKKLPAANYNNLRYLIKFMAKLAEHQ 403

  Fly   425 DLNKMTSSNLAIVFGPNFLWSRST-STSLEEIAP-----INAFVDFVLQNHKDIYLIDVN 478
            ::||||.||:|||.|||.||::|. .|||.::|.     :.:.|:.:|....:|:..||:
 Frog   404 EVNKMTPSNIAIVLGPNLLWAKSDGETSLLDMASASPIIVVSVVEGLLNCAANIFPEDVD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP68F	NP_001401037.1	CRAL_TRIO_2	119..242	CDD:463965	23/123 (19%)
		RhoGAP-p50rhoGAP	278..473	CDD:239869	66/202 (33%)
sh3bp1	XP_031756949.1	BAR	16..250	CDD:472257	41/201 (20%)
		RhoGAP	263..462	CDD:470621	66/202 (33%)