Protein Alignment CG5645 and Kri1

DIOPT Version :10

• Sequence 1: NP_648550.1
• Gene: CG5645 / 39382
• FlyBaseID: FBgn0036254
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001385635.1
• Gene: Kri1 / 687183
• RGDID: 1588903
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 852
• Identity: 318/852 - (37%)
• Similarity: 437/852 - (51%)
• Gaps: 196/852 - (23%)

  Fly    18 LSTNKDYAKTYNILRKKELLQKYKDR---GLDVSESEFDSDSSSSEEDEVDPKFDQDFFKTLSSL 79
            |..|..:|..|:..|::|.||:.|||   ..|.|:|..:|| ||.|..|.||:.::||::|||.|
  Rat    10 LKVNAAFAARYSRYREREELQRLKDRYGDRDDGSDSSSESD-SSDEHVEFDPQQERDFYRTLSLL 73

  Fly    80 KSKDPCIYDKGTKFF---SESSGDEDDKDGEAPKKKKKAKPVTLKDYERKVILEHNGKFESSDEE 141
            |.|||.||.|...|:   :|:|..|.:::..|..|:||.:|:.|||||||||||..||:...|..
  Rat    74 KKKDPRIYQKDATFYQRTAEASSSESEEESAALGKQKKVQPMYLKDYERKVILEKEGKYVDEDNS 138

  Fly   142 QQEKEHEELQRAQSPSAVEEERRLKAEFRKVMNKEDDSEDEEFG----GIFKKRSKTKEQTAAEE 202
            ..|.....||...:.|.:||:|:||..||..:  ||.|:::..|    |:.:|.:|:.|:.|.|:
  Rat   139 DGESVDHRLQETATKSYIEEQRQLKESFRAFV--EDSSDEDSAGEGGSGLLQKHTKSGEEKAQED 201

  Fly   203 ADFAKWLAGKQAEIQETDK-KQLEPLKQYWSSNKLTQGESFLRDYILNKGYANTDESAIPTYDEI 266
            .|:.:||.| |.||..::. |:|..||:||::.:|.:||.|||||||||.| ..||......:.:
  Rat   202 VDYLEWLKG-QKEIDSSESLKELTHLKEYWNNPELDEGEQFLRDYILNKRY-EEDEEEETEEERV 264

  Fly   267 VGEAAPL----SEDEQE--LEKQAEFEHKYNFRFEEPDADFIKRYPRTIEQSLRRTDDKRKEKRK 325
            :|....|    |.||.|  |:||.:|||||||||||||:..:|.|||:|..|:||.||:|||||:
  Rat   265 LGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDDRRKEKRE 329

  Fly   326 ELKERKDQEKQQKMKELELVKEMKRKEIDEKIRKLKAVTGNDELGFRDEELEEDFDPAAHDRRMQ 390
            |.:|||.:||.:|.:||:.:|.:|||||..|:.||:.||||:.||..:::||:|||||.||:.||
  Rat   330 ETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRQVTGNETLGLEEQDLEDDFDPAQHDQLMQ 394

  Fly   391 ELFDDEYYNVDEGEEKPECPSDIDELVLED---WDNY-DPRQHANGGGEDYEGHCEDDDFNMDCD 451
            :.|.|.:|...| ||||:..   :|..|||   ||.: .|.|  ||.....|.||||.|||||.|
  Rat   395 KCFGDAFYGTVE-EEKPQFE---EEEGLEDDWNWDTWGGPEQ--NGAWSQQELHCEDPDFNMDAD 453

  Fly   452 YDPSTAKEQLQQELIENTRGRKGRKGRRNRFMEMIQAEKPAFNPEDEKTYSEYIDEYYQMDCEDI 516
            ||||..:::|::      ....|::.|::.|...:..|||.|:|.| ||:.||:||||::|.|||
  Rat   454 YDPSQPRKKLRE------APTSGKRKRKSPFAAAVGQEKPMFDPGD-KTFEEYLDEYYRLDYEDI 511

  Fly   517 IGDQPCRFKYVETTPNDFGLTIEEILLAKNKELNQWASLKKAVQNRPEHVEKKEQRLYKMKAKNE 581
            |.|.||||||....|.||||:.||||.|.:||||:|.||||....|.|..|.:|||.|..||::.
  Rat   512 IDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRAYSQKAQSV 576

  Fly   582 DLKRKIFKSLYGEGSDDEEQPAEEKPEVTPAEATAPAENGQVSTEGLSKSKRKRLKRKAAAAAAS 646
            ..||:|||||           .:|:.|: |.|||           |.|.||        |::...
  Rat   577 WKKRQIFKSL-----------CQEEVEM-PTEAT-----------GKSPSK--------ASSQVQ 610

  Fly   647 APKVLKEESDSKDPKEADGSTEDVQAESSKKKVDTPSKKGKDDANQETKNSPQSTEKTKNNNALK 711
            .|.          |..|.|  :..|||.|..|            .:|..::|..
  Rat   611 LPM----------PSAAGG--KKPQAELSGAK------------EEELAHTPCP----------- 640

  Fly   712 NNKKEPKNVQNGFQKPQNQANKSAKTKSNQPFKTTESAPAKAEKSNGNNPFNKPQSKSQQRQELP 776
                         :||.:|..||.|.:...|..|.
  Rat   641 -------------EKPASQKQKSKKARLLGPTVTL------------------------------ 662

  Fly   777 PIHKNQGGNKKGPRNANGTNPFKKSNQKPSAPFPAKKTNNFKAKNKQNNNSGITDDRLKAYGINP 841
                  ||:|                                          .:..||:|:|:||
  Rat   663 ------GGHK------------------------------------------FSRQRLQAFGLNP 679

  Fly   842 RKFHKRE 848
            ::.|.|:
  Rat   680 KRLHFRQ 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5645	NP_648550.1	Kri1	333..423	CDD:461569	44/92 (48%)
		Kri1_C	499..587	CDD:463756	50/87 (57%)
Kri1	NP_001385635.1	Kri1	318..427	CDD:461569	58/112 (52%)
		Kri1_C	494..582	CDD:463756	50/87 (57%)