Protein Alignment DEF8 and def8

DIOPT Version :10

• Sequence 1: NP_648549.1
• Gene: DEF8 / 39381
• FlyBaseID: FBgn0046296
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_073785148.1
• Gene: def8 / 492523
• ZFINID: ZDB-GENE-041114-96
• Length: 439
• Species: Danio rerio
• Alignment Length: 418
• Identity: 144/418 - (34%)
• Similarity: 232/418 - (55%)
• Gaps: 35/418 - (8%)

  Fly    54 SEESGPQGAEYRALPIPASLVREQWR----LIFTSDANIQDLQAAIAHCRDLVLLSEELSEERRW 114
            |:.|.|        |:...|..:.:.    |...||  ::.|:.||..|:.|:|...|.||:::.
Zfish    48 SQNSDP--------PMDLGLAEDHFSRPVGLFVASD--VEQLKLAIEECKRLILELPEHSEKQKD 102

  Fly   115 LVRHLVDLRYSLQELEEAQEQHSLSSDMVVMNAIRAVVGHHFVPHHPHHGKRNRLQAAAKRNYCD 179
            .|..|:.||..||||::.:|...         .::.::.|.|          ::.::.:.:..||
Zfish   103 AVVKLIHLRLKLQELQDPEEDEP---------NLQVMLEHRF----------SKEKSKSVKQMCD 148

  Fly   180 HCTTIIWSVVQNSYVCSDCGFLVHQKCIDGVKRVCAHVLVSERQHPISEICPEIGLASQGYKCAE 244
            .|:||||.::|..|.|:.|.:..|.||:..:.:.|....||.:......|||||||..|.|:|:|
Zfish   149 KCSTIIWGLIQTWYTCTGCYYRCHSKCMSLINKPCVRSKVSHQSEYELNICPEIGLDKQDYRCSE 213

  Fly   245 CGTMLNIKNTWIEPRLCDYSGLYYCPRCNWNDSNFIPARIIHNWDFSPRRVSRTALQEIRLFLNK 309
            |.|.::::....|.|.|||:|.|||..|:|||:..:|||:||||:|.||:|.|::::.:.|.:.:
Zfish   214 CRTPISLRGIPNEARQCDYTGQYYCSSCHWNDTAIVPARVIHNWEFEPRKVCRSSMRYLALMMPR 278

  Fly   310 PLIRLEEDNPKLFVFVEKLCAVKKLRQNLVHMRHYLAACKIASELKLVDQQLGVRRHLAQSNEFY 374
            |::||:|.||.||.|||.|..::||||:::.|:.|...||.|.|.:|: ..|..|:|..::::.|
Zfish   279 PVLRLKEINPLLFNFVEDLVEIRKLRQDILLMKPYFITCKEAMEARLL-LHLQDRQHFVENDDMY 342

  Fly   375 SLSDLSQVESGALSEFLQGVFKAFNDHIR-SCPMCLAQAYICEICSNNEVIFPFDDGCIKCDQCN 438
            ||.||....:|.||..|..:...|..||: .|..|.|:.::||:|...:.:||||.....|..|.
Zfish   343 SLQDLIDTSNGRLSCSLTEIHTTFAKHIKLDCEKCQAKGFVCELCKEGDSLFPFDSHTSVCHDCL 407

  Fly   439 SIFHRVCLTRKNMICPKCIRIQERRLQL 466
            ::|||.|....:.:||.|.|:.|.:|::
Zfish   408 AVFHRDCYYDNSTMCPHCERMLEHKLEV 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DEF8	NP_648549.1	C1_DEF8	<173..219	CDD:410369	15/45 (33%)
		zf-RING_9	259..461	CDD:464030	83/202 (41%)
def8	XP_073785148.1	None