Protein Alignment DEF8 and Rubcnl

DIOPT Version :10

• Sequence 1: NP_648549.1
• Gene: DEF8 / 39381
• FlyBaseID: FBgn0046296
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_008769127.1
• Gene: Rubcnl / 290403
• RGDID: 1304929
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 126/517 - (24%)
• Similarity: 202/517 - (39%)
• Gaps: 130/517 - (25%)

  Fly    16 AQLINESASNL---LHASSTLGSTVGLGGSGSTGSGSEA------------GGSEESGPQG-AEY 64
            |.||.....||   |.:....||:.....|.|.|:|:|.            ..|..:|.:| |..
  Rat   235 ADLIISVIENLKCSLLSQQQPGSSGTEEASRSCGTGAEVTFHTHAKQEPDPSASSHTGCEGCAAL 299

  Fly    65 RALPIPASL----------VREQWRLIFTSDANIQDL---------QAAIAHCRDLVLLSEELSE 110
            :..|:..:|          ..:..:|:........||         .:..|.|:..:.|:..|:.
  Rat   300 QVSPVAEALSYCPVAIEACTLDLNKLVILELGKSNDLTEGCRGSYSSSESATCKSNLSLAGLLAR 364

  Fly   111 E------RRWLVRH---------LVDLRYSLQELEEAQEQHSLSSDMV--VMNAIRAVVGHHFVP 158
            |      :.|::..         |:.....:.|.|:|:|:...|.|..  ||...|......:||
  Rat   365 ELFRGFYKYWMLSEEVTRQPPGSLIPASSGVGEEEQAEEELDSSVDTAREVMLKSRVPGTEDWVP 429

  Fly   159 HHPHHGKRNRLQAAAKRNYCDHCTTIIWSVVQNSYVCSDCGFLVHQKCIDGVKRVCAHVLVSERQ 223
                                ..|..|:               .||..    |||
  Rat   430 --------------------PPCQIIL---------------TVHPP----VKR----------- 444

  Fly   224 HPISEICPEIGLASQGYKCAECGTMLNIKNTWIEP------RLCDYSGLYYCPRCNWNDSNFIPA 282
                    :|.:.:|.:.||.|||.       |:|      |.|:|.|.|:|.||:.:..:.|||
  Rat   445 --------DIAVVAQNFFCAGCGTP-------IQPKFVKRLRYCEYLGKYFCDRCHSSAESCIPA 494

  Fly   283 RIIHNWDFSPRRVSRTALQEIRLFLNKPLIRLEEDNPKLFVFVEKLCAVKKLRQNLVHMRHYLAA 347
            ||:..|||...:||..:...:....::|:..|...:..|:..|::|..||.:::.|.|::..|..
  Rat   495 RILLMWDFRKYQVSDFSKWLLDSIWHQPIFNLLSGHHSLYAKVKELDRVKDIQEQLFHIKKLLKT 559

  Fly   348 CKIA-SELKLVDQQLGVRRHLAQSNEFYSLSDLSQVESGALSEFLQGVFKAFNDHIRSCPMCLAQ 411
            |:.| |.||..:|   |..||......:|:.|..:.:.|.|:..|:.:.:|...|:.||.:|..:
  Rat   560 CRFADSVLKEFEQ---VPSHLTDECHMFSMDDFLRTKKGLLAPLLKDILRASLAHVDSCELCQGK 621

  Fly   412 AYICEICSNNEVIFPFDD-GCIKCDQCNSIFHRVCLTRKNMICPKCIRIQERRLQLDRMKST 472
            .:|||.|.:..|||||.. .|.:|..|.:.||:.|.  ::..||:|.||..||...:.:..|
  Rat   622 GFICEFCQSTTVIFPFQTMTCRRCAGCRACFHKQCF--QSSRCPRCARIIARRQHSESLTGT 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DEF8	NP_648549.1	C1_DEF8	<173..219	CDD:410369	7/45 (16%)
		zf-RING_9	259..461	CDD:464030	67/203 (33%)
Rubcnl	XP_008769127.1	zf-RING_9	471..668	CDD:464030	65/201 (32%)