Protein Alignment Ir68b and gria1a

DIOPT Version :10

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_991161.1
• Gene: gria1a / 798689
• ZFINID: ZDB-GENE-020125-1
• Length: 914
• Species: Danio rerio
• Alignment Length: 619
• Identity: 97/619 - (15%)
• Similarity: 178/619 - (28%)
• Gaps: 258/619 - (41%)

  Fly   163 PFAWG-GLQV--------IQRLDGEVPYARKVKDLRGYPLRFSMFTDPLMAMPRSPVETAGYQAV 218
            |..|| |:.:        |:.|.|.:.:..|     |....:|:....|  .|..| :..||...
Zfish   326 PAPWGQGIDIQRALQQVRIEGLTGHIQFNEK-----GRRTNYSISVMEL--RPTGP-KKVGYWNE 382

  Fly   219 DGVAARVVGEMLNASVTYVFPEDNESYGRCLPNGNYTGVVSDIV--------GGHTHFAPNSRFV 275
            |        |...::..|: |..||:||  |.|..|  :|:.|:        ..|.||..|.::.
Zfish   383 D--------EKFVSTAAYM-PGSNETYG--LQNRTY--IVTTILESPYVMLKKNHEHFTGNDKYE 434

  Fly   276 LDCI---------------------------------WPAV--EVLY------------------ 287
            ..|:                                 |..:  |::|
Zfish   435 GYCVELAAEIAKHVGYHYILKIVADGKYGARDAETMMWNGMVGELVYGKADVAVAPLTITLVREE 499

  Fly   288 ------PYTRRNLHLVV--PASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRL----- 339
                  |:....:.:::  |..: :|....|:......:|..::...:.|.:|.:::.|.
Zfish   500 VIDFSKPFMSLGISIMIKKPTKS-KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW 563

  Fly   340 ----------------------------------QRRIPRRGVIQFQATWYEI-------LEMFG 363
                                              |.:....|:  |.:.|:.:       .::..
Zfish   564 HADDCEDGAEENPNQPSSSSAQPGQNQQNQNQQSQEQTNEFGI--FNSLWFSLGAFMQQGCDISP 626

  Fly   364 KTHVGEPAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHI 428
            ::..|...|.:            |..|:.::.:.|.|.|.:..........::..:||
Zfish   627 RSLSGRIVGGV------------WWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL------- 672

  Fly   429 YAVTTMYDAVRSALTEHQYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAF-----IMRDFHARD 488
                       :..||..||.|:       .|....::     ||.:.|.|     .|:......
Zfish   673 -----------AKQTEIAYGTLD-------AGSTKEFF-----RRSKIAVFEKMWSYMKSADPSV 714

  Fly   489 FLAITYD------SQAERPAYHIAREYLRSMICTYI-----------------------LPRGSP 524
            |:..|.:      ....:.||     .|.|.:..||                       .|:|||
Zfish   715 FVKTTDEGVMRVRKSKGKYAY-----LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSP 774

  Fly   525 FLHRLESLYSGFLEHGFFEH-----WRQMDLITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRN 584
            ..:.:........|.|..:.     |.                      |:.:..||..:  .::
Zfish   775 LRNPVNLAVLKLNEQGLLDKLKNKWWY----------------------DKGECGSGGGD--SKD 815

  Fly   585 KKVVLTLDILQGAFYLWSVGIGISCLGFAVEHAH 618
            |...|:|..:.|.||:...|:|::.|...||..:
Zfish   816 KTSALSLSNVAGVFYILIGGLGLAMLVALVEFCY 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	None
gria1a	NP_991161.1	Periplasmic_Binding_Protein_type1	26..390	CDD:471960	17/79 (22%)
		PBP2_iGluR_AMPA_GluR1	404..806	CDD:270447	60/475 (13%)
		Lig_chan	536..835	CDD:459656	52/371 (14%)