Protein Alignment Ir68b and grin2bb

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 594
• Identity: 119/594 - (20%)
• Similarity: 210/594 - (35%)
• Gaps: 155/594 - (26%)

  Fly   129 GRHQLLRL-FRGSWAKK----------LLYGLAIT--GRENGTFDFDPFAWGGLQVIQRLDGEVP 180
            |.|.||:. ..|:..||          |.|.:.:|  || |.:|..|.|......||..|:.|..
Zfish   386 GPHTLLKSGCHGAPDKKGSKSGNPNEVLRYLMNVTFEGR-NLSFSEDGFQMHPKLVIILLNKERQ 449

  Fly   181 YARKVKDLRG--------YPLRFSMFTD---------PLMAMPRSP-VETAGYQAVDGVAAR--- 224
            |.|..|...|        :| ||.:::|         .::.:..:| |.......:.|...|
Zfish   450 YERVGKWENGSLAMKYHVWP-RFELYSDAEEREDDHLSIVTLEEAPFVIVEDVDPLSGTCMRNTV 513

  Fly   225 ----------VVGE--------------------MLNASVTY-VFPEDNESYGRCLPNGNYTGVV 258
                      :.|:                    ..:...|| ::...|..:|:.: ||.:.|:|
Zfish   514 PCRKQLKLQNLTGDSGIYIKRCCKGFCIDILKKIAKSVKFTYDLYLVTNGKHGKKI-NGTWNGMV 577

  Fly   259 SDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVVPAS--AIQPEYLIFVRVFRRTVWYL 321
            .::|..:.|.|..|..:.:.....::...|:....:.::|..|  .:.|.  .|:..|...||.:
Zfish   578 GEVVLKNAHMAVGSLTINEERSEVIDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVM 640

  Fly   322 LLVTLLVV----VLVFWVMQRL-------QRRIPRRGVIQF---QATWYEILEMFG-----KTHV 367
            :.|.||:|    |.||.....:       ..|.|  |...|   :|.|.    ::|     ...|
Zfish   641 MFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREP--GGPSFTIGKAIWL----LWGLVFNNSVPV 699

  Fly   368 GEPAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVT 432
            ..|.|..|     :..:..|..|:.:....|.|.|.:..::..|.:||..:.|......:.::..
Zfish   700 QNPKGTTS-----KIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVTGLSDKKFQHPNDFSPP 759

  Fly   433 TMYDAVRSALTEHQYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAITYDSQ 497
            ..:..|.:..||..   :.|..:::. ...||::|..|..       .:....:....|..||
Zfish   760 FRFGTVPNGSTERN---IRNNYKEMH-SYMTSFHQKNVNE-------ALHSLKSGKLDAFIYD-- 811

  Fly   498 AERPAYHIAREYLRSMICTYILPRGSPFLHRLESLYSGFL------------EHGFFEHW-RQMD 549
                          :.:..|:..|....  :|.::.||::            :.|    | |.:|
Zfish   812 --------------AAVLNYMAGRDEGC--KLVTIGSGYIFATTGYGIAIQKDSG----WKRAVD 856

  Fly   550 L-ITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDILQGAFYLWSVGIGISCLGFA 613
            | |.::....:.|| ||.|.......:..||:....    |.:|.:.|.||:....:.:|.:.|.
Zfish   857 LAILQLFGDGEMEE-LEALWLTGICHNEKNEVMSSQ----LDVDNMAGVFYMLGAAMALSLITFI 916

  Fly   614 VEHAHWFWR 622
            .||. ::|:
Zfish   917 AEHL-FYWQ 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	55/302 (18%)
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..470	CDD:107373	25/85 (29%)
		ANF_receptor	138..442	CDD:279440	17/56 (30%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	79/447 (18%)
		Lig_chan	636..908	CDD:278489	63/320 (20%)
		NMDAR2_C	919..1770	CDD:287527	2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591437
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930