Protein Alignment Ir68b and grik2

DIOPT Version :10

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001410875.1
• Gene: grik2 / 556013
• ZFINID: ZDB-GENE-080414-1
• Length: 908
• Species: Danio rerio
• Alignment Length: 664
• Identity: 109/664 - (16%)
• Similarity: 205/664 - (30%)
• Gaps: 194/664 - (29%)

  Fly    50 DYSALELDLYRCVGSRLP----VITRNMEAHELEPFRRTDSLSIFQIPAAEKGDSLVRRILD--- 107
            |..||:::.||..|..:.    :.|.|.:...:     .:..|:.::.|..|.||   .:||
Zfish   260 DLFALDVEPYRYSGVNMTGFRILNTENSQVSSI-----IEKWSMERLQAPPKPDS---GLLDGFM 316

  Fly   108 ----------------------MLNPHQRRKHMHKYLFVWPNAGRHQLLRLFRGSWAKKLLYGLA 150
                                  .:.....:.:.||   .|....|...| :....|.       .
Zfish   317 TTDAALMYDAVHVVAVAVQQSPQITVSSLQCNRHK---PWRFGNRFMTL-IKEAHWD-------G 370

  Fly   151 ITG-----RENG---TFDFDPFA-----------W---GGLQVIQRLDGEVPYARKVKDLRGYPL 193
            :||     |.||   .||.|..:           |   .||.:.:...|:.  |.....|....|
Zfish   371 LTGRINFNRTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTENQKGKT--ANVTDSLSNRSL 433

  Fly   194 RFS-MFTDPLMAMPRSPVETAGYQAVDGVAARVVGEM---LNASVTYVFPEDNESYGRCLPNGNY 254
            ..| :..:|.:...:|.....|....:|....::.|:   |.........||.....:...:|.:
Zfish   434 VVSTILEEPYVMFKKSDKPLYGNDRFEGYCVDLLRELAAILGFGYELRLVEDGRYGAQDESSGQW 498

  Fly   255 TGVVSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVV-PASAIQPEYLIFVRVFRRTV 318
            .|:|.:::......|.....:.......::...|:....:.::. ..:...|....|:......:
Zfish   499 NGMVRELMDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDI 563

  Fly   319 WYLLLVTLLVVVLVFWVMQRLQRRIPRRGVIQFQATWY---------EILE---------MFGKT 365
            |..:|:..|.|..|.:|:.|..           ...||         :::|         .||..
Zfish   564 WMYILLAYLGVSCVLFVIARFS-----------PYEWYNPHPCNPDSDVVENNFTLLNSFWFGVG 617

  Fly   366 HVGEPAGRLSSFSSMRTFLMG--WILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHI 428
            .:.:....|.. .::.|.::|  |..|:.::.:.|.|.|.:.......|..:|..|||
Zfish   618 ALMQQGSELMP-KALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDL------- 674

  Fly   429 YAVTTMYDAVRSALTEHQYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAIT 493
                       :..|:.:||::|:.|..      |.:.:..:...|:...|:....|:  .:..:
Zfish   675 -----------AKQTKIEYGVVEDGSTM------TFFKKTKISTYDKMWEFMSSRRHS--VMVKS 720

  Fly   494 YDSQAERPAYHIAREYLRSMICTYI-------------------------LPRGSPFLHRLESLY 533
            .:...||.   :..:|...|..|.|                         .|.|||:..::....
Zfish   721 IEEGIERV---LTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKAYGVGTPMGSPYRDKITIAI 782

  Fly   534 SGFLEHG----FFEHWRQMDLITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDIL 594
            ....|.|    ..|.|      .|....|:.|            :..::.|.::|         :
Zfish   783 LQLQEEGKLHMMKEKW------WRGNGCPEEE------------NKEASALGVQN---------I 820

  Fly   595 QGAFYLWSVGIGIS 608
            .|.|.:.:.|:.:|
Zfish   821 GGIFIVLAAGLVLS 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	None
grik2	NP_001410875.1	PBP1_iGluR_Kainate	37..414	CDD:380605	32/172 (19%)
		Periplasmic_Binding_Protein_Type_2	430..800	CDD:473866	65/416 (16%)