Protein Alignment Ir68b and Grik

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 119/661 - (18%)
• Similarity: 198/661 - (29%)
• Gaps: 212/661 - (32%)

  Fly    69 ITRNMEAH--ELEPFRRTDS----LSIFQIPAAEKGDSLVRRILDMLNPHQR------------- 114
            |..|::.|  :|||::...:    |.:.. |.:|:...:.:.:.:...|.|.
  Fly   243 IIGNLDWHTMDLEPYQHAGTNITGLRLVS-PDSEQVQEVAKALYESEEPFQNVSCPLTNSMALVY 306

  Fly   115 ---------RKHMHKYLFVWPNAGRHQLLRLFR---------GSWAK-----KLLYGLAITGREN 156
                     .||::                 ||         .:|.|     ..:..|.:.|. .
  Fly   307 DGVQLLAETYKHVN-----------------FRPVALSCNDDSAWDKGYTLVNYMKSLTLNGL-T 353

  Fly   157 GTFDFD-------------PFAWGGLQVIQRLDGE--------VPYARKVKDLRGYPLR----FS 196
            |...||             ..|..|:|.|.:..||        .|......|:|....:    .:
  Fly   354 GPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVIT 418

  Fly   197 MFTDPLMAMPRSPVETAGYQAVDGVAARVVGEM---LNASVTYVFPEDNESYGRCLP-NGNYTGV 257
            ..::|...:..:..:..|....:|....::.|:   |..|.|:...|||: ||...| .|.:.|:
  Fly   419 AISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNK-YGGIDPKTGEWNGM 482

  Fly   258 VSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVVPASAIQPEYLI-FVRVFRRTVWYL 321
            :.:|:............:.......|:...|:....:.::......:|..|. |:..|...||..
  Fly   483 LREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLW 547

  Fly   322 LLVTLLVVVLVFWVMQRLQRRIPRRGVIQFQATW---YEILEMFGKTHVGEPAGRLSSFS----- 378
            |.:..:.|.:..:|:.||.           .|.|   |..:|        ||....:.||
  Fly   548 LGLAYMGVSISMFVLGRLS-----------PAEWDNPYPCIE--------EPTELENQFSFANCL 593

  Fly   379 -------------------SMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDL--- 421
                               |.|.....|..|:.:|.:.|.|.|.:.....|....::..|||
  Fly   594 WFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKN 658

  Fly   422 ---VHLDVHIYAVTTMYDAVRSALTEHQYGLLENR---SRQLPLGIATSYYQPVVRRRDRRAAFI 480
               |:....|...|..:      ..|..|...:..   .|..|..:..:..:.|.|..:...||:
  Fly   659 KGGVNYGAKIGGATFNF------FKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFL 717

  Fly   481 MRDFHARDFLAITYDSQAERPAYHIAREYLRSMICT------YILPRGSPFLHRLESLYSGFLEH 539
            |..                     ...||:....||      .:..:|.....|....|...|..
  Fly   718 MES---------------------TTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQ 761

  Fly   540 GFFEHWRQMDLITRV-----------GASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDI 593
            ...| .::..|:|::           ||..||:|           |||:..|.|.|
  Fly   762 AVLE-MQEQGLLTKMKTKWWQEKRGGGACSDADE-----------DSGAVALEISN--------- 805

  Fly   594 LQGAFYLWSVG 604
            |.|.|.:..||
  Fly   806 LGGVFLVMGVG 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	62/325 (19%)
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	28/166 (17%)
		ANF_receptor	53..374	CDD:279440	22/149 (15%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	72/417 (17%)
		Lig_chan	543..816	CDD:278489	64/339 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930