Protein Alignment Ir68b and gria4a

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 794
• Identity: 127/794 - (15%)
• Similarity: 236/794 - (29%)
• Gaps: 310/794 - (39%)

  Fly    17 YALAEIACRIAVEQNVQVTYLYRCASCPASF-DADYSALELDLYRCVGSRLPVITRNMEAHELEP 80
            ||:.:.....|.:...||:     |.|..:| ||.|..|..||.|....:..:        :||
Zfish   159 YAVLQAIMEKAGQNGWQVS-----AICVENFNDASYRRLLEDLDRRQEKKFVI--------DLE- 209

  Fly    81 FRRTDSLSIFQIPAAEKGDSLVRRILDMLNPHQRRKHMHKYLFVWPNAGRHQLLRLFRGSWAKKL 145
                          ||:..:::.:|:.:      .||:..|.::..|.|       |:....::.
Zfish   210 --------------AERLQNILEQIVSV------GKHVKGYHYIVANLG-------FKDISLERF 247

  Fly   146 LYGLA-ITGRENGTFDFD-PFAWGGLQVIQR-----------------------LDGEVPYARKV 185
            ::|.| :||.:  ..||. |..   ::::||                       .||.:..|...
Zfish   248 MHGGANVTGFQ--LVDFSKPMV---IKLMQRWNKLDQREYPGSESPPRYTSSLTYDGVLVMAEAF 307

  Fly   186 KDLRGYPLRFSM--FTDPLMAMPRSP-------VETAGYQAVDGVAARVVGEMLNASVTY----- 236
            ::||...:..|.  .....:|.|.:|       ..|.....:.|:...:..:.....|.|
Zfish   308 RNLRRQKIDISRRGNAGDCLANPAAPWNQGIDMERTLKQVRIQGLTGNIQFDHYGRRVNYTMDVF 372

  Fly   237 -------------------VFPEDNESYGRCLPNGNYTGVVSDIVGG--------HTHFAPNSRF 274
                               |..::..|.|......|.|.:|:.|:.|        ...:..|.:|
Zfish   373 ELKSNGPRKIGYWNDLDKLVLVQNELSMGNDSAMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQF 437

  Fly   275 -----------------------VLD----------CIWPAV--EVLY----------------- 287
                                   |||          .||..:  |::|
Zfish   438 EGYCVDLASEVAKHIGIKYKISIVLDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLAITLVRE 502

  Fly   288 -------PYTRRNLHLVV--PASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRLQRRI 343
                   |:....:.:::  |..: :|....|:......:|..::...:.|.:|.:::.|..
Zfish   503 EVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS--- 563

  Fly   344 PRRGVIQFQATWY--EILEMFGKTHVGEPAGRLSSFSSMRTFLMG-------------------- 386
                    ...|:  |..|........:|......|:|: .|.:|
Zfish   564 --------PYEWHTEEPEEGSDGPPSDQPPNEFGIFNSL-WFSLGAFMQQGCDFTPRSLSGRIVG 619

  Fly   387 --WILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTEHQYGL 449
              |..|:.::.:.|.|.|.:..........::..:||                  :..||..||.
Zfish   620 GVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL------------------AKQTEIAYGT 666

  Fly   450 LENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAITYDSQAERPAYHIAREYLRS-- 512
            |::.|                          .::|..|..:|:          |.....|::|
Zfish   667 LDSGS--------------------------TKEFFRRSKIAV----------YEKMWSYMKSAE 695

  Fly   513 -MICTYILPRGSPFLHRLESLYSGFLEHGFFEHWRQ---MDLITRVGASPDAE------------ 561
             .:.|.....|...:.:.:..|:..||....|:..|   .|.: :||.:.|::
Zfish   696 PTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTM-KVGGNLDSKGYGVATPKGSQL 759

  Fly   562 ----------------------EFLEDLGDQTDTDSGSNELAIRNKKVVLTLDILQGAFYLWSVG 604
                                  ::..|.|:....||||.:    .....|:|..:.|.||:...|
Zfish   760 GTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKD----KSSQALSLSNVAGVFYILVGG 820

  Fly   605 IGISCLGFAVEHAH 618
            :|::.|...||..:
Zfish   821 LGLAMLVALVEFCY 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	51/337 (15%)
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..393	CDD:107383	48/279 (17%)
		ANF_receptor	34..375	CDD:279440	48/261 (18%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	62/449 (14%)
		Lig_chan	540..821	CDD:278489	53/351 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591800
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930