DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir68b and Ir52a

DIOPT Version :9

Sequence 1:	NP_648548.1	Gene:	Ir68b / 39378	FlyBaseID:	FBgn0036250	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_611041.2	Gene:	Ir52a / 36715	FlyBaseID:	FBgn0034023	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	106/483 - (21%)
Similarity:	188/483 - (38%)	Gaps:	124/483 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 YARKVKDLRGYPLRFSMFTDPLMAMPRSPV---ETAGYQAVDGVAARVV---GEMLNASVTYVFP 239
            |....:::||..:|  ...|.|  :||:.:   |.:|...:.|....::   .:.|||.:.::
  Fly   177 YIENFQNMRGATIR--TVADSL--VPRTILYRDEKSGETKMMGYLGHMINTYAQKLNAKLHFI-- 235

  Fly   240 EDNESYGRCLPN----GNYTGVVSDIVGGHTHFAPNSRFV-LDCIWPAVEVLYPYTRRNLHLVVP 299
             |....|...|:    .|:  |..|||...|..|.:.:|. :|.:|      |||......|:||
  Fly   236 -DTSKLGAKKPSVLDIMNW--VNEDIVDIGTALASSLQFKNMDSVW------YPYLLTGYCLMVP 291

  Fly   300 ASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRLQRRIPRRGVIQFQATWYEILEMFGK 364
            ..|..|..|::..:    |..|:|..:.|::.:|.|:           :|..|...::.|.:
  Fly   292 VPAKMPYNLVYSMI----VDPLVLSIIFVMLCLFSVL-----------IIYTQHLSWKNLTL--- 338

  Fly   365 THVGEPAGRLSSFSSMRTFL-------------MGWILF-----SYVLSTIYFAKLESGFVRPSY 411
                  |..|.:..|:|..|             :..|:|     |.:::|:|.|.|:|.|.:|..
  Fly   339 ------ANILLNDKSLRGLLGQSFPFPPNPSKHLKLIIFVLCFASVMITTMYEAYLQSYFTQPPS 397

  Fly   412 EEQVDRVDD---------LVHLDVHIYAVTTMYDAVRSALTEHQYGLLENRSRQLPL--GIATSY 465
            |..:....|         :..|:|::  :|::.::....::|....:.::.|..|.|  ...||:
  Fly   398 EPYIRSFRDIGNSSLKMAISRLEVNV--LTSLNNSHFREISEDHLLIFDDLSEYLVLRDSFNTSF 460

  Fly   466 YQPV-VRRRDRRAAFIMRDFHARDFLAITYDSQAE---RPAYHIARE--YLRSMICTYILPRGSP 524
            ..|| |.|.:                  .|:.|.:   .||:::|..  :.:.|:.:..|.|..|
  Fly   461 IFPVSVDRWN------------------GYEEQQKLFAEPAFYLATNLCFNQFMLFSPPLRRYLP 507

  Fly   525 FLHRLESLYSGFLEHGFFEHWRQMDLI--TRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKV 587
            ..|..|.......|.|....|:....|  .|:|.:.     :|||..:            ||::|
  Fly   508 HRHLFEDHMMRQHEFGLVTFWKSQSFIEMVRLGLAS-----MEDLSRK------------RNEEV 555

  Fly   588 VLTLDILQGAFYLWSVGIGISCLGFAVE 615
            .|.||.:.....|:...:.||...|.:|
  Fly   556 SLLLDDISWILKLYLGAMFISSFCFILE 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	62/310 (20%)
Ir52a	NP_611041.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100