Protein Alignment Ir68b and gria4b

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 787
• Identity: 125/787 - (15%)
• Similarity: 238/787 - (30%)
• Gaps: 295/787 - (37%)

  Fly    17 YALAEIACRIAVEQNVQVTYLYRCASCPASF-DADYSALELDLYRCVGSRLPVITRNMEAHELEP 80
            |::.:.....|.:...||:     |.|..:| ||.|..|..||
Zfish   164 YSILQAIMEKAGQNGWQVS-----AICVENFNDASYRQLLEDL---------------------- 201

  Fly    81 FRRTDSLSIFQIPAAEKGDSLVRRILDMLNPHQRRKHMHKYLFVWPNAGRHQLLRLFRGSWAKKL 145
            .||.:...:..: .||:.::::.:|:.:      .||:..|.::..|.|       |:....::.
Zfish   202 DRRQEKTFVIDL-EAERLNNMLEQIVSV------GKHVKGYHYIMANLG-------FKDINLERF 252

  Fly   146 LYGLA-ITG-----------------------RENGTFDFDP-----FAWGGLQV---------- 171
            ::|.| :||                       ||....|..|     ..:.|:.|
Zfish   253 MHGGANVTGFQLVDFSNPMVIKLMQRWNKLDQREYPGSDAPPKYTSALTYDGVMVMAEAFRNLRR 317

  Fly   172 ------------------------------------IQRLDGEVP---YARKVK------DLRGY 191
                                                :|.|.|.|.   |.|:|.      :|:..
Zfish   318 QKVDISRRGIAGDCLANPAAPWNQGIDMERTLKQVHLQGLTGNVQFDHYGRRVNYTMDVFELKSN 382

  Fly   192 -PLRFSMFTDP---LMAMPRS--PVETAGYQAVDGVAARVV-GEMLNASVTYVFPEDNESY-GRC 248
             |.|...:.|.   ::....:  |.||:|.:....:...:: |..:.....:...|.||.| |.|
Zfish   383 GPRRIGYWNDADKLVLTQDHALLPNETSGMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQYEGYC 447

  Fly   249 -------------------LPNGNY----------TGVVSDIVGGHTHFAPNSRFVLDCIWPAVE 284
                               :|:|.|          .|:|.::|.|....|.....:.......::
Zfish   448 VDLASEIAKHIGFKYKISIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLTITLVREEVID 512

  Fly   285 VLYPYTRRNLHLVV--PASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRL-----QRR 342
            ...|:....:.:::  |..: :|....|:......:|..::...:.|.:|.:::.|.     ...
Zfish   513 FSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTE 576

  Fly   343 IPRRGVIQ------------FQATWYEILEMFGKTHVGEPAGRLSSFSSMRTFLMG--WILFSYV 393
            .|..|...            |.:.|:.:.....:       |...|..|:...::|  |..|:.:
Zfish   577 EPEEGTDGLPSDQPPNEFGIFNSLWFSLGAFMQQ-------GCDISPRSLSGRIVGGVWWFFTLI 634

  Fly   394 LSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTEHQYGLLENRSRQLP 458
            :.:.|.|.|.:..........::..:||                  :..|:..||.|::.|
Zfish   635 IISSYTANLAAFLTVERMVSPIESAEDL------------------AKQTDIAYGTLDSGS---- 677

  Fly   459 LGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAITYDSQAERPAYHIAREYLRS---MICTYILP 520
                                  .::|..|..:|:          |.....|::|   .:.|....
Zfish   678 ----------------------TKEFFRRSKIAV----------YEKMWSYMKSAEPTVFTKTTA 710

  Fly   521 RGSPFLHRLESLYSGFLEHGFFEHWRQ---MDLITRVGASPDAEEFLEDLGDQTDTDSGS----- 577
            .|...:.:.:..|:..||....|:..|   .|.: :||.:.|::      |....|..||
Zfish   711 EGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTM-KVGGNLDSK------GYGVATPKGSQLRSA 768

  Fly   578 --------NELAIRNK-----------------------KVVLTLDILQGAFYLWSVGIGISCLG 611
                    ||..:.:|                       ...|:|..:.|.||:...|:|::.|.
Zfish   769 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGGEKDKSSQALSLSNVAGVFYILVGGLGLAMLV 833

  Fly   612 FAVEHAH 618
            ..:|..:
Zfish   834 ALIEFCY 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	51/334 (15%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	45/274 (16%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	67/447 (15%)
		Lig_chan	546..827	CDD:306551	53/348 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930