DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir68b and GluRIIE

DIOPT Version :9

Sequence 1:	NP_648548.1	Gene:	Ir68b / 39378	FlyBaseID:	FBgn0036250	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001036733.1	Gene:	GluRIIE / 318623	FlyBaseID:	FBgn0051201	Length:	897	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	104/492 - (21%)
Similarity:	176/492 - (35%)	Gaps:	122/492 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 LMAMPRSP----VET----AGYQAVDGVAARVVGEMLN-ASVTYVFPEDNESYGRCLPNGN-YTG 256
            |:::|..|    |||    .|....:|....::.|:.: ....:.|......||....:.| .||
  Fly   425 LLSVPNKPYAQLVETYKQLEGNSQYEGYGVDLIKELADKLGFNFTFVNGGNDYGSYNKSTNESTG 489

  Fly   257 VVSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVV----PASAIQPEYLIFVRVFRRT 317
            ::.:|:.|....|.....:......|::...|:  .||.:.:    |..| .||...|:..|...
  Fly   490 MLREIMTGRADLAITDLTITSEREQALDFTIPF--MNLGIAILYLKPQKA-TPELFTFMDPFSEE 551

  Fly   318 VWYLLLVTLLVVVLVFWVMQRLQR----------RIPRRGVIQF---QATWYEILEMFGK-THVG 368
            ||:.|..:.|.|.|.|:::.||..          ..|.....||   .:.|:....:..: :.:|
  Fly   552 VWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQQGSEIG 616

  Fly   369 EPAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLV-HLDVHIYAV- 431
            ..|      .|.||....|..|:.::.:.|.|.|.:.......:..::.||||. :.|..:|..
  Fly   617 PKA------LSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAK 675

  Fly   432 ---TTMYDAVRSALTEHQYGLLENRSRQLPLGIATSYYQPVVR-RRDRRAAFIMRDFHARDFLAI 492
               :|....:.||  |.:|..:.....:.|..:.....:.|.| :.:...||:|      :..:|
  Fly   676 KTGSTRNFFMTSA--EERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLM------ESTSI 732

  Fly   493 TYDSQAE-----------RPAYHIAREYLRSMICTYILPRGSPFLHR-------LESLYSGFLEH 539
            .|:::.|           ...|.||..              ..:.||       ||....|.||.
  Fly   733 EYNTKRECNLKKIGDALDEKGYGIAMR--------------KDWPHRGKFNNALLELQEQGVLEK 783

  Fly   540 GFFEHWRQMDLITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDILQGAFYLWSVG 604
            ...:.|.:      ||....|.:  ||..|.|..|                ::.|:|.|::..||
  Fly   784 MKNKWWNE------VGTGICATK--EDAPDATPLD----------------MNNLEGVFFVLLVG 824

  Fly   605 IGISCLG----------FAVEHAHWFWRRQTLRNAVE 631
               ||..          |.::.||.:  |..||:|::
  Fly   825 ---SCCALLYGIISWVLFVMKKAHHY--RVPLRDALK 856

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	61/311 (20%)
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377
		ANF_receptor	51..382	CDD:279440
		PBP2_iGluR_Kainate	419..790	CDD:270432	81/395 (21%)
		Lig_chan	551..824	CDD:278489	65/324 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462884
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930