Protein Alignment Ir68b and GRID2

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 676
• Identity: 128/676 - (18%)
• Similarity: 227/676 - (33%)
• Gaps: 193/676 - (28%)

  Fly    30 QNVQVTYLYRCASCPASFDADYSALELDLYRCVGSRLPVITRNMEAHE-----LEPFRR------ 83
            ||::::.||...:.....:|.:..||...:..:.| |..|.:|.:..:     ||..::
Human   330 QNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMAS-LSCIRKNSKPWQGGRSMLETIKKGGVSGL 393

  Fly    84 TDSLSI----------FQIPAAEKGDSLVRRILDMLNPHQRRKHMHKYLFVWPNAGRHQLLRLFR 138
            |..|..          |:|.....|:.|.|.:    ..::|.:.......:||     ||
Human   394 TGELEFGENGGNPNVHFEILGTNYGEELGRGV----RKNERIRPQGSTGKIWP-----QL----- 444

  Fly   139 GSWAKKLLYGLAITGRENGTFDFDPFAWGGLQVIQRLDGEVPYARKVKDLRGYPLR--------F 195
            |.|.       .:||                     |:|.:...:...::||..||        |
Human   445 GCWN-------PVTG---------------------LNGSLTDKKLENNMRGVVLRVVTVLEEPF 481

  Fly   196 SMFTDPLMAMPRSPVETAGYQAVDGVAARVVGEMLN----ASVTYVFPEDNESYGRCLPNGNYTG 256
            .|.::.::..|:.      ||   |.:..|:..:.|    ....||.|:  ..||....:|.:.|
Human   482 VMVSENVLGKPKK------YQ---GFSIDVLDALSNYLGFNYEIYVAPD--HKYGSPQEDGTWNG 535

  Fly   257 VVSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVVPASAIQPEYLI----FVRVFRRT 317
            :|.::|........::.    .|.|..|.:..:|.|.:...|.....:.|..:    .:..|..:
Human   536 LVGELVFKRADIGISAL----TITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLS 596

  Fly   318 VWYLLLVTLLVVVLVFWVMQRLQRRIPR------RGVIQFQATWYEILEMFGKTHVGEPAGRLSS 376
            :|..:..|:|:|.|:.:::..|..  ||      .....:.:.|:    ::|.  ..:..|.:..
Human   597 LWACIAGTVLLVGLLVYLLNWLNP--PRLQMGSMTSTTLYNSMWF----VYGS--FVQQGGEVPY 653

  Fly   377 FSSMRTFLMG-WILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDL---------VHLDVHIYAV 431
            .:.....:|| |.||:.::.:.|.|.|.:.......|..:..:.||         ..||..:|..
Human   654 TTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEH 718

  Fly   432 TTMYDA---VRSALTEHQYGLL------ENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHAR 487
            ..|...   .|.::....:.::      ||...:...||....|        ...||:. |....
Human   719 VRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKY--------GNYAFVW-DAAVL 774

  Fly   488 DFLAI--------TYDSQAERPAYHIAREYLRSMICTYILPRGSP----FLHRLESLYSG----F 536
            :::||        |..:......|.||            |..|||    |..|:..|...    .
Human   775 EYVAINDPDCSFYTIGNTVADRGYGIA------------LQHGSPYRDVFSQRILELQQNGDMDI 827

  Fly   537 LEHGFFEHWRQMDLITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDILQGAFYLW 601
            |:|.::....|.||.:.|                 ||......|.|::         ..|.|.:.
Human   828 LKHKWWPKNGQCDLYSSV-----------------DTKQKGGALDIKS---------FAGVFCIL 866

  Fly   602 SVGIGISCLGFAVEHAHWFWRRQTLR 627
            :.||.:||  |......|:.:|:..|
Human   867 AAGIVLSC--FIAMLETWWNKRKGSR 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	57/314 (18%)
GRID2	XP_011530195.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910